CAS 658-48-0

α-Methyl-p-tyrosine

Description:

α-Methyl-p-tyrosine, also known as metyrosine, is a non-proteinogenic amino acid that serves as a competitive inhibitor of the enzyme tyrosine hydroxylase, which is crucial in the biosynthesis of catecholamines such as dopamine, norepinephrine, and epinephrine. Its chemical formula is C10H13NO3, and it features a phenolic hydroxyl group, a methyl group on the alpha carbon, and an amino group, contributing to its structural and functional properties. This compound is typically a white to off-white crystalline powder and is soluble in water and alcohol, making it suitable for various pharmaceutical applications. Metyrosine is primarily used in clinical settings to manage conditions associated with excessive catecholamine production, such as pheochromocytoma. Its mechanism of action involves reducing catecholamine synthesis, thereby lowering blood pressure and alleviating symptoms related to catecholamine excess. As with any pharmacological agent, its use should be monitored for potential side effects, including sedation and gastrointestinal disturbances.

Formula: C₁₀H₁₃NO₃

InChI: InChI=1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)

InChI key: InChIKey=NHTGHBARYWONDQ-UHFFFAOYSA-N

SMILES: C(C(C(O)=O)(C)N)C1=CC=C(O)C=C1

Synonyms:

• (2R)-3-(4-hydroxyphenyl)-2-(methylammonio)propanoate
• (±)-α-Methyl-<span class="text-smallcaps">D</smallcap><smallcap>L</span>-tyrosine
• (±)-α-Methyl-p-tyrosine
• 2-(4-Hydroxybenzyl)-2-aminopropanoic acid
• 2-Amino-3-(4-hydroxy-phenyl)-2-methyl-propionic acid
• 2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid
• <span class="text-smallcaps">DL</span>-2-Methyl-p-tyrosine
• <span class="text-smallcaps">DL</span>-α-Methyl-p-tyrosine
• <span class="text-smallcaps">DL</span>-α-Methyltyrosine
• A-Methyl-Dl-P-Tyrosine
• DL-~-Methyl-p-tyrosine
• L 1-79
• Racemetirosine
• Sm 88
• Tyrosine, α-methyl-
• alpha-MT
• alpha-Methyl-DL-tyrosine
• alpha-methyl-D-tyrosine
• dl-Metyrosine
• α-MPT
• α-Methyl-<span class="text-smallcaps">DL</span>-tyrosine
• α-Methyltyrosine
• DL-α-Methyltyrosine

D,L-α-methyltyrosine

CAS: 658-48-0

Formula: C₁₀H₁₃NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 195.2151

Ref: IN-DA003NTW

α-Methyl-DL-tyrosine

CAS: 658-48-0

Formula: (HO)C₆H₄CH₂C(CH₃)(NH₂)CO₂H

Purity: ≥ 97.5%

Color and Shape: White to off-white powder

Molecular weight: 195.22

Ref: 7W-GC1425

2-Amino-3-(4-Hydroxyphenyl)-2-Methylpropanoic Acid

CAS: 658-48-0

2-Amino-3-(4-Hydroxyphenyl)-2-Methylpropanoic Acid

Purity: 97%

Molecular weight: 195.22g/mol

Ref: 54-OR1010255

DL-Metirosine-13C-d3 HCl

CAS: 30625-05-9, 658-48-0

Formula: C₉₁₃CH₁₀D₃NO₃·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 199.23 36.46

Ref: 4Z-M-150002

Racemetirosine

CAS: 658-48-0

Racemetirosine

Purity: ≥98%

Molecular weight: 195.22g/mol

Ref: 54-BUP06567

DL-Metirosine-13C-d3

CAS: 30625-05-9, 658-48-0

Formula: C₉₁₃CH₁₀D₃NO₃

Molecular weight: 199.23

Ref: 4Z-M-150010

Metirosine

CAS: 658-48-0

Formula: C₁₀H₁₃NO₃

Molecular weight: 195.22

Ref: 4Z-M-150001

α-Methyl-D,L-tyrosine

Controlled Product

CAS: 658-48-0

Formula: C₁₀H₁₃NO₃

Color and Shape: Neat

Molecular weight: 195.22

Ref: TR-M332685

2-P-HYDROXYPHENYLMETHYL-DL-ALANINE

CAS: 658-48-0

Formula: C₁₀H₁₃NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 195.218

Ref: 10-F303151

α-Methyl-DL-tyrosine

CAS: 658-48-0

Please enquire for more information about alpha-Methyl-DL-tyrosine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₀H₁₃NO₃

Purity: Min. 97.5 Area-%

Molecular weight: 195.22 g/mol

Ref: 3D-M-5185

Racemetirosine

CAS: 658-48-0

Racemetirosine is a Tyrosine 3-monooxygenase inhibitor, and inhibits the synthesis of catecholamines consequently.

Formula: C₁₀H₁₃NO₃

Purity: 98.73%

Color and Shape: Off-White Fine Powder

Molecular weight: 195.22

Ref: TM-T20700