CAS 65802-56-4

4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrate

Description:

4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrate is an organic compound characterized by its pyrimidine ring structure, which is a six-membered aromatic ring containing two nitrogen atoms. This compound features an amino group (-NH2), a hydroxy group (-OH), and a mercapto group (-SH) attached to the pyrimidine ring, contributing to its reactivity and potential biological activity. The presence of these functional groups suggests that it may participate in various chemical reactions, including nucleophilic substitutions and redox reactions. As a monohydrate, it contains one molecule of water per formula unit, which can influence its solubility and stability. This compound is of interest in pharmaceutical and biochemical research, particularly for its potential applications in medicinal chemistry. Its CAS number, 65802-56-4, allows for easy identification and reference in scientific literature and databases. Overall, 4-Amino-6-hydroxy-2-mercaptopyrimidine monohydrate is notable for its unique structural features and potential utility in various chemical and biological contexts.

Formula: C₄H₇N₃O₂S

InChI: InChI=1/C4H5N3OS.H2O/c5-2-1-3(8)7-4(9)6-2;/h1H,(H4,5,6,7,8,9);1H2

SMILES: c1c(N)nc(nc1O)S.O

Synonyms:

• 6-Amino-2-thiouracil monohydrate
• 6-Amino-2-thiouracil
• 6-amino-2-thioxo-2,3-dihydropyrimidin-4(1H)-one hydrate
• 6-Amino-2-mercaptopyrimidin-4-ol monohydrate
• 4-Amino-6-Hydroxy-2-Mercaptopyrimidine

6-Amino-2-thioxo-2,3-dihydropyrimidin-4(1H)-one hydrate

CAS: 65802-56-4

Formula: C₄H₇N₃O₂S

Purity: 95%

Color and Shape: Solid

Molecular weight: 161.1823

Ref: IN-DA003KQD

6-Amino-2-thiouracil monohydrate

CAS: 65802-56-4

6-Amino-2-thiouracil monohydrate

Formula: C₄H₅N₃OS·H₂O

Purity: ≥95%

Color and Shape: off white powder

Molecular weight: 161.18g/mol

Ref: 54-OR2651

6-Amino-4-hydroxy-2-mercaptopyrimidine monohydrate

CAS: 65802-56-4

6-Amino-4-hydroxy-2-mercaptopyrimidine monohydrate (6AP) is a chemical compound that has been shown to have potent antibacterial activity against Gram-positive bacteria. It is also effective at inhibiting the growth of S. aureus, both in vitro and in vivo. 6AP can be used as an alternative treatment for cancer, where it inhibits the growth of tumor cells by blocking ferrocene, which plays an important role in cancer cell proliferation and survival. The efficacy of 6AP against bacterial infections has been demonstrated in vitro with a variety of Gram-positive pathogens, including S. aureus, Streptococcus pneumoniae, Enterococcus faecalis, and Bacillus anthracis.

Formula: C₄H₅N₃OS•H₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 161.18 g/mol

Ref: 3D-FA08191

6-Amino-2-thiouracil monohydrate

CAS: 65802-56-4

Formula: C₄H₇N₃O₂S

Purity: 95%+

Color and Shape: Crystalline

Molecular weight: 161.18

Ref: 10-F036345

6-Amino-2-thiouracil Hydrate

Controlled Product

CAS: 65802-56-4

Applications Derivatives of 6-Amino-2-thiouracil as novel, potent, and selective A3 adenosine receptor antagonists.
References Ji, X., et al.: Drug Dev. Res., 33, 51 (1994), Poulsen, S., et al.: Bioorg. Med. Chem., 6, 619 (1998), Fredholm, B., et al.: Pharmacol. Rev., 53, 527 (2001), Gessi, S., et al.: Clin. Cancer Res., 10, 5895 (2004), Moro, S., et al.: Med. Chem. Res., 26, 131 (2006), Tafi, A., et al.: J. Med. Chem., 49, 4085 (2006),

Formula: C₄H₅N₃OS·H₂O

Color and Shape: Neat

Molecular weight: 161.18

Ref: TR-A630455