CAS 65807-02-5
:Goserelin
Description:
Goserelin is a synthetic peptide analog of gonadotropin-releasing hormone (GnRH), primarily used in the treatment of hormone-sensitive conditions such as prostate cancer, breast cancer, and endometriosis. It functions as a GnRH agonist, initially stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which subsequently leads to a decrease in sex hormone production through negative feedback mechanisms. Goserelin is administered via subcutaneous implant, providing a sustained release of the drug over time. Its chemical structure includes a sequence of amino acids that mimic the natural hormone, allowing it to bind to GnRH receptors effectively. The substance is characterized by its ability to suppress gonadal steroidogenesis, making it valuable in managing conditions that are exacerbated by sex hormones. Common side effects may include hot flashes, decreased libido, and potential bone density loss due to prolonged hormone suppression. Overall, Goserelin represents a critical therapeutic option in the management of various hormone-dependent diseases.
Formula:C59H84N18O14
InChI:InChI=1/C59H84N18O14/c1-31(2)22-40(49(82)68-39(12-8-20-64-57(60)61)56(89)77-21-9-13-46(77)55(88)75-76-58(62)90)69-54(87)45(29-91-59(3,4)5)74-50(83)41(23-32-14-16-35(79)17-15-32)70-53(86)44(28-78)73-51(84)42(24-33-26-65-37-11-7-6-10-36(33)37)71-52(85)43(25-34-27-63-30-66-34)72-48(81)38-18-19-47(80)67-38/h6-7,10-11,14-17,26-27,30-31,38-46,65,78-79H,8-9,12-13,18-25,28-29H2,1-5H3,(H,63,66)(H,67,80)(H,68,82)(H,69,87)(H,70,86)(H,71,85)(H,72,81)(H,73,84)(H,74,83)(H,75,88)(H4,60,61,64)(H3,62,76,90)/t38-,39-,40-,41-,42-,43-,44-,45+,46-/m0/s1
Synonyms:- 5-oxoprolylhistidyl-N-[18,18-diamino-7-(tert-butoxymethyl)-13-({2-[(2-carbamoylhydrazinyl)carbonyl]pyrrolidin-1-yl}carbonyl)-4-(4-hydroxybenzyl)-1-(hydroxymethyl)-10-(2-methylpropyl)-2,5,8,11-tetraoxo-3,6,9,12,17-pentaazaoctadec-17-en-1-yl]tryptophanamide
- 5-oxo-L-prolyl-L-histidyl-N-[(1S,4S,7R,10S,13S)-18,18-diamino-7-(tert-butoxymethyl)-13-({(2S)-2-[(2-carbamoylhydrazino)carbonyl]pyrrolidin-1-yl}carbonyl)-4-(4-hydroxybenzyl)-1-(hydroxymethyl)-10-(2-methylpropyl)-2,5,8,11-tetraoxo-3,6,9,12,17-pentaazaoctadec-17-en-1-yl]-L-tryptophanamide
- 1-9-Luteinizing hormone-releasing factor (swine), 6-[O-(1,1-dimethylethyl)-D-serine]-, 2-(aminocarbonyl)hydrazide
- Decapeptide I
- Ici 118630
- Luteinizing hormone-releasing factor (pig), 6-[O-(1,1-dimethylethyl)-D-serine]-10-deglycinamide-, 2-(aminocarbonyl)hydrazide
- Zoladex
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Found 8 products.
(D-Ser(tBu)⁶,Azagly¹⁰)-LHRH (free base)
CAS:<p>Bachem ID: 4073798.</p>Formula:C59H84N18O14Purity:98.7%Color and Shape:White LyophilisateMolecular weight:1269.43Goserelin-d7 Tritrifluoroacetate
CAS:Formula:C59H77D7N18O14·3C2HF3O2Color and Shape:White To Off-White SolidMolecular weight:1276.48 3*114.02Goserelin Acetate
CAS:Formula:C59H84N18O14Purity:95%~99%Color and Shape:White to Off-white PowderMolecular weight:1269.42Goserelin
CAS:<p>Goserelin is a hormone that is used to treat certain types of breast cancer in women who are premenopausal. It has been shown that Goserelin can be used for the treatment of endometriosis and radiation therapy for cancer. Goserelin is also used to prevent recurrence of prostate cancer in men who have had surgery or radiation therapy.<br>Goserelin is also used as an anticancer agent for the treatment of platinum-resistant ovarian cancer in women who are premenopausal and cannot be treated with other agents. The mechanism by which it works is not fully understood, but it has been shown to inhibit the growth of tumor cells in vitro and in vivo.</p>Formula:C59H84N18O14Purity:Min. 95%Molecular weight:1,269.41 g/mol
