CAS 658084-23-2

(3Z)-N-(3-chlorophenyl)-3-({3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylidene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide

Description:

The chemical substance with the name "(3Z)-N-(3-chlorophenyl)-3-({3,5-dimethyl-4-[(4-methylpiperazin-1-yl)carbonyl]-1H-pyrrol-2-yl}methylidene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide" and CAS number "658084-23-2" is a complex organic compound characterized by its multi-functional groups and structural diversity. It features a sulfonamide moiety, which is known for its biological activity, particularly in medicinal chemistry. The presence of a chlorophenyl group suggests potential interactions with biological targets, while the pyrrole and piperazine components may contribute to its pharmacological properties. The compound's structure indicates it may exhibit specific stereochemistry, as denoted by the "(3Z)" configuration, which can influence its reactivity and binding affinity. Overall, this substance is likely to be of interest in drug development, particularly for conditions where sulfonamide derivatives have shown efficacy. Its detailed characteristics, including solubility, stability, and biological activity, would require empirical investigation to fully understand its potential applications.

Formula: C₂₈H₃₀ClN₅O₄S

InChI: InChI=1/C28H30ClN5O4S/c1-17-25(30-18(2)26(17)28(36)34-12-10-32(3)11-13-34)16-23-22-15-21(8-9-24(22)31-27(23)35)39(37,38)33(4)20-7-5-6-19(29)14-20/h5-9,14-16,30H,10-13H2,1-4H3,(H,31,35)/b23-16-

SMILES: Cc1c(/C=C\2/c3cc(ccc3N=C2O)S(=O)(=O)N(C)c2cccc(c2)Cl)[nH]c(C)c1C(=O)N1CCN(C)CC1

Synonyms:

• Su11274
• Su 11274

SU 11274

CAS: 658084-23-2

Formula: C₂₈H₃₀ClN₅O₄S

Molecular weight: 568.09

Ref: 7W-GL1480

SU11274

CAS: 658084-23-2

SU11274

Purity: ≥98%

Molecular weight: 568.09g/mol

Ref: 54-BUP08717

SU 11274

CAS: 658084-23-2

MET tyrosine kinase inhibitor; anti-proliferative; pro-apoptotic

Formula: C₂₈H₃₀ClN₅O₄S

Purity: Min. 95%

Color and Shape: Yellow To Orange Solid

Molecular weight: 568.09 g/mol

Ref: 3D-FS65178

SU11274

CAS: 658084-23-2

SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.

Formula: C₂₈H₃₀ClN₅O₄S

Purity: 98.62% - 99.53%

Color and Shape: Orange Powder

Molecular weight: 568.09

Ref: TM-T6154