CAS 6584-40-3

2-(thiophen-2-yl)-2,3-dihydro-1H-perimidine

Description:

2-(Thiophen-2-yl)-2,3-dihydro-1H-perimidine, with the CAS number 6584-40-3, is an organic compound characterized by its unique structure that includes a perimidine core fused with a thiophene ring. This compound typically exhibits properties associated with heterocyclic compounds, such as potential aromaticity due to the presence of the thiophene moiety. It is likely to be a solid at room temperature, with moderate solubility in organic solvents, reflecting the influence of its heteroatoms and ring structures on its polarity. The presence of nitrogen atoms in the perimidine structure may impart basicity and influence its reactivity in various chemical reactions, including nucleophilic substitutions and electrophilic additions. Additionally, compounds like this can exhibit interesting electronic properties, making them of interest in materials science and organic electronics. Its potential applications may extend to pharmaceuticals, agrochemicals, or as intermediates in organic synthesis, although specific applications would depend on further research into its biological activity and chemical behavior.

Formula: C₁₅H₁₂N₂S

InChI: InChI=1/C15H12N2S/c1-4-10-5-2-7-12-14(10)11(6-1)16-15(17-12)13-8-3-9-18-13/h1-9,15-17H

Synonyms:

• 2-Thiophen-2-yl-2,3-dihydro-1H-perimidine

2-(Thiophen-2-yl)-2,3-dihydro-1H-perimidine

CAS: 6584-40-3

The compound 2-(thiophen-2-yl)-2,3-dihydro-1H-perimidine has been found to exhibit potent acetylcholinesterase (AChE) inhibitory activity. AChE is the target of organophosphate and carbamate insecticides and nerve agents. The inhibition study revealed that 2-(thiophen-2-yl)-2,3-dihydro-1H-perimidine binds to the active site of AChE with a strong binding affinity. The crystal structures of this molecule have been determined by x-ray crystallography, which revealed that it has a dipole moment. This molecule was also found to have an absorbance at frequencies in the fingerprint region, which can be used for identification purposes. The theory behind its structure was determined by vibrational spectroscopy techniques as well as analyses of its crystal structures.

Formula: C₁₅H₁₂N₂S

Purity: Min. 95%

Molecular weight: 252.3 g/mol

Ref: 3D-GAA58440