CAS 6586-04-5

toluidine blue

Description:

Toluidine blue, also known as toluidine blue O, is a synthetic dye belonging to the thiazine class of compounds. It is characterized by its deep blue color and is commonly used as a biological stain in histology and cytology due to its ability to bind to nucleic acids and certain proteins. The dye exhibits metachromasia, meaning it can change color when bound to different types of tissues, which enhances its utility in microscopy. Toluidine blue is soluble in water and alcohol, making it versatile for various applications. In addition to its staining properties, it has been employed in medical diagnostics, particularly in identifying certain types of tumors and in the detection of mast cells. The compound has a relatively low toxicity profile, but safety precautions should still be observed during handling. Its chemical structure includes an amino group, contributing to its basicity and interaction with biological molecules. Overall, toluidine blue is a valuable tool in both research and clinical settings for visualizing cellular components.

Formula: C₁₅H₁₆ClN₃S

InChI: InChI=1/C15H15N3S.ClH/c1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12(14)17-13;/h4-8,16H,1-3H3;1H

SMILES: Cc1cc2c(cc1=N)sc1cc(ccc1n2)N(C)C.Cl

Synonyms:

• N-(7-amino-8-methyl-3H-phenothiazin-3-ylidene)-N-methylmethanaminium chloride

TOLUIDINE BLUE FOR MICROSCOPY

CAS: 6586-04-5

Formula: C₁₅H₁₆Cl₃N₃SZn

Color and Shape: Solid

Molecular weight: 442.1116

Ref: IN-DA00FCO1