CAS 65899-73-2
:Tioconazole
Description:
Tioconazole is an antifungal agent primarily used in the treatment of various fungal infections, particularly those caused by dermatophytes and yeast. It belongs to the imidazole class of antifungals and functions by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, thereby disrupting their integrity and function. Tioconazole is typically available in topical formulations, such as creams and ointments, and is often used for conditions like athlete's foot, ringworm, and vaginal yeast infections. The substance is characterized by its relatively low solubility in water, which enhances its effectiveness when applied directly to affected areas. Tioconazole exhibits a broad spectrum of activity against various fungi, making it a versatile option in antifungal therapy. Additionally, it has a favorable safety profile, with minimal systemic absorption when used topically, resulting in fewer side effects compared to systemic antifungal treatments. As with any medication, it is essential to follow usage guidelines and consult healthcare professionals for appropriate indications and potential interactions.
Formula:C16H13Cl3N2OS
InChI:InChI=1S/C16H13Cl3N2OS/c17-12-1-2-13(14(18)7-12)15(8-21-5-4-20-10-21)22-9-11-3-6-23-16(11)19/h1-7,10,15H,8-9H2
InChI key:InChIKey=QXHHHPZILQDDPS-UHFFFAOYSA-N
SMILES:C(CN1C=CN=C1)(OCC2=C(Cl)SC=C2)C3=C(Cl)C=C(Cl)C=C3
Synonyms:- 1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl) ethyl]-1H-imidazole
- 1-[2-[(2-Chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)-ethyl]imidazole
- 1-{2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
- 1H-Imidazole, 1-[2-[(2-chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-
- Fungibacid
- Gyno-Trosyd
- New Straitus U
- Tioconazol
- Trosyd
- Trosyl
- Vagistat
- Vagistat 1
- Zoniden
- Tioconazole
- See more synonyms
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Found 16 products.
Tioconazole
CAS:TioconazoleFormula:C16H13Cl3N2OSPurity:99.6%Color and Shape:WhiteMolecular weight:385.98142TIOCONAZOLE FOR SYSTEM SUITABILITY CRS
CAS:<p>TIOCONAZOLE FOR SYSTEM SUITABILITY CRS</p>Formula:C16H13Cl3N2OSColor and Shape:Crystalline Powder. White. Powder.Molecular weight:387.7112Tioconazole
CAS:<p>Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi</p>Formula:C16H13Cl3N2OSColor and Shape:PowderMolecular weight:385.981421-{2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
CAS:Formula:C16H13Cl3N2OSPurity:98%Color and Shape:SolidMolecular weight:387.7112Tioconazole
CAS:<p>Tioconazole (Vagistat) is a synthetic imidazole derivative, inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols.</p>Formula:C16H13Cl3N2OSPurity:99.57%Color and Shape:SolidMolecular weight:387.71Tioconazole, Ph. Eur. grade
CAS:Formula:C16H13Cl3N2OSPurity:≤ 0.1%Color and Shape:White to almost white powderMolecular weight:387.71Tioconazole
CAS:Formula:C16H13Cl3N2OSPurity:≥ 98.0% (dried basis)Color and Shape:White or almost white powder or crystalsMolecular weight:387.71Tioconazole
CAS:Controlled Product<p>Applications Tioconazole is an antifungal that is more active than Fluconazole (F421000) or Voriconazole (V760000) against Candida glabrata mutant strains. Antifungal (topical).<br>References Jevons, S., et al.: Antimicrob. Agents Chemother., 15, 597 (1979), Clayton, Y.M., et al.: Clin. Exp. Dermatol., 7, 543 (1982), Marriott, M.S., et al.: Dermatologica, 166, 1 (1983),<br></p>Formula:C16H13Cl3N2OSColor and Shape:WhiteMolecular weight:387.71Tioconazole
CAS:<p>Tioconazole is an antifungal agent, which is a synthetic derivative of imidazole with broad-spectrum activity against fungi. This compound is chemically synthesized through complex organic reactions to enhance its antimycotic efficacy. Tioconazole functions by inhibiting the synthesis of ergosterol, an essential component of the fungal cell membrane. By disrupting the ergosterol biosynthesis pathway, tioconazole destabilizes the fungal cell membrane, leading to increased permeability and eventual cell death.</p>Formula:C16H13Cl3N2OSPurity:Min. 95%Molecular weight:387.71 g/mol
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