CAS 659-40-5

Hexamidine diisethionate

Description:

Hexamidine diisethionate is an organic compound characterized by its use as an antiseptic and antimicrobial agent. It is a white to off-white crystalline powder that is soluble in water, making it suitable for various pharmaceutical and cosmetic applications. The compound features a hexamidine backbone, which is a symmetrical structure with two isethionate groups that enhance its solubility and stability. Hexamidine diisethionate exhibits broad-spectrum antimicrobial activity, effective against a range of bacteria and fungi, which makes it valuable in formulations aimed at treating skin infections and preserving products. Additionally, it is known for its low toxicity profile, making it a safer alternative in topical applications. The compound is often included in formulations for wound care, personal hygiene products, and as a preservative in cosmetics. Its mechanism of action involves disrupting microbial cell membranes, leading to cell death. Overall, hexamidine diisethionate is recognized for its efficacy and safety in various applications within the pharmaceutical and cosmetic industries.

Formula: C₂₀H₂₆N₄O₂·2C₂H₆O₄S

InChI: InChI=1S/C20H26N4O2.C2H6O4S/c21-19(22)15-5-9-17(10-6-15)25-13-3-1-2-4-14-26-18-11-7-16(8-12-18)20(23)24;3-1-2-7(4,5)6/h5-12H,1-4,13-14H2,(H3,21,22)(H3,23,24);3H,1-2H2,(H,4,5,6)

InChI key: InChIKey=SUXLANSZRSDYOX-UHFFFAOYSA-N

SMILES: O(CCCCCCOC1=CC=C(C(=N)N)C=C1)C2=CC=C(C(=N)N)C=C2.C(S(=O)(=O)O)CO

Synonyms:

• 2-Hydroxyethanesulfonic Acid - 4,4'-[Hexane-1,6-Diylbis(Oxy)]Dibenzenecarboximidamide (1:1)
• 2-Hydroxyethanesulfonic Acid - 4,4'-[Hexane-1,6-Diylbis(Oxy)]Dibenzenecarboximidamide (2:1)
• 2-Hydroxyethanesulphonic Acid, Compound With 4,4'-[Hexane-1,6-Diylbis(Oxy)]Bis[Benzenecarboxamidine] (2:1)
• 2535Rp
• Benzamidine, 4,4′-(hexamethylenedioxy)di-, bis(2-hydroxyethanesulfonate)
• Benzamidine, 4,4′-(hexamethylenedioxy)di-, diisethionate
• Benzenecarboximidamide, 4,4′-[1,6-hexanediylbis(oxy)]bis-, bis(2-hydroxyethanesulfonate)
• Desomedine
• Elastab HP 100
• Elestab HP 100
• Esomedina
• Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4′-(hexamethylenedioxy)dibenzamidine
• Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4′-(hexamethylenedioxy)dibenzamidine (2:1)
• Ethanesulfonic acid, 2-hydroxy-, compd. with 4,4′-[1,6-hexanediylbis(oxy)]bis[benzenecarboximidamide] (2:1)
• Hexamethylenedioxy-4,4′-dibenzamidinebis(hydroxy-2-ethanesulfonate)
• Hexamidine diisethionate
• Hexamidine isethionate
• Hexomedine
• NSC 115848
• Ophtamedine
• Rp 2535

HEXAMIDINE DIISETIONATE CRS

CAS: 659-40-5

HEXAMIDINE DIISETIONATE CRS

Formula: C₂₂H₃₂N₄O₆S

Color and Shape: White. Light Yellow. Powder.

Molecular weight: 480.5777

Ref: 41-H0330000

4,4'-(Hexane-1,6-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate)

CAS: 659-40-5

4,4'-(Hexane-1,6-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate)

Purity: 97%

Molecular weight: 606.72g/mol

Ref: 54-OR1055182

Hexamidine Diisetionate

CAS: 659-40-5

Formula: C₂₀H₂₆N₄O₂·2C₂H₆O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 354.46 2*126.13

Ref: 4Z-H-024011

Hexamidine diisethionate

CAS: 659-40-5

Formula: C₂₀H₂₆N₄O₂·2C₂H₆O₄S

Purity: 98.5 - 101.5 % (dried basis)

Color and Shape: White or pale yellow powder

Molecular weight: 606.71

Ref: 7W-GK9166

Hexamidine diisetionate

CAS: 659-40-5

Formula: C₂₀H₂₆N₄O₂C₂H₆O₄S

Color and Shape: Neat

Molecular weight: 606.71

Ref: 04-C14194800

Hexamidine diisethionate

CAS: 659-40-5

Hexamidine diisethionate is a synergistic compound that has been used as a model system to study the effects of benzalkonium chloride on mammalian DNA. It is also used as an antimicrobial agent in products such as skin care and polymerase chain reactions, which can be found in laboratories and hospitals. Hexamidine diisethionate works by reacting with the nitrogen atoms of organic molecules to form nitrosamines, which are reactive and highly cytotoxic. These nitrosamines inhibit the DNA polymerase of human pathogens and other microorganisms, preventing their growth. They also prevent glycol esters from being hydrolyzed to glycols, which would cause them to be toxic themselves.

Formula: C₂₄H₃₈N₄O₁₀S₂

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 606.71 g/mol

Ref: 3D-FH147080