CAS 6590-96-1

2,4-Dichlorophenyl isothiocyanate

Description:

2,4-Dichlorophenyl isothiocyanate, with the CAS number 6590-96-1, is an organic compound characterized by its isothiocyanate functional group attached to a dichlorophenyl moiety. It typically appears as a yellow to brown liquid or solid, depending on its purity and temperature. This compound is known for its pungent odor and is soluble in organic solvents such as acetone and ether, but has limited solubility in water. It is primarily used in chemical synthesis and as a reagent in various organic reactions, particularly in the preparation of thioureas and other nitrogen-containing compounds. Additionally, it has applications in biological research, particularly in studies involving protein labeling and enzyme inhibition. Due to its reactive nature, 2,4-Dichlorophenyl isothiocyanate can pose health risks, including irritation to the skin, eyes, and respiratory system, necessitating proper handling and safety precautions in laboratory settings.

Formula: C₇H₃Cl₂NS

InChI: InChI=1S/C7H3Cl2NS/c8-5-1-2-7(10-4-11)6(9)3-5/h1-3H

InChI key: InChIKey=WVBNZZHGECFCSH-UHFFFAOYSA-N

SMILES: N(=C=S)C1=C(Cl)C=C(Cl)C=C1

Synonyms:

• Isothiocyanic acid, 2,4-dichlorophenyl ester
• 2,4-Dichloro-1-isothiocyanatobenzene
• AF 100
• 2,4-Dichlorophenyl isothiocyanate
• Benzene, 2,4-dichloro-1-isothiocyanato-

2,4-Dichlorophenyl isothiocyanate, 97%

CAS: 6590-96-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₃Cl₂NS

Purity: 97%

Color and Shape: Crystals or powder or crystalline powder or lumpy/fused solid, White to cream or brown or yellow

Molecular weight: 204.07

Ref: 02-B20178

2,4-Dichlorophenyl isothiocyanate

CAS: 6590-96-1

Formula: C₇H₃Cl₂NS

Purity: 95%

Color and Shape: Solid

Molecular weight: 204.0764

Ref: IN-DA003FRJ

2,4-dichlorophenyl isothiocyanate

CAS: 6590-96-1

2,4-dichlorophenyl isothiocyanate

Purity: 99%

Ref: 54-OR28866

2,4-Dichlorophenyl Isothiocyanate

CAS: 6590-96-1

Formula: C₇H₃Cl₂NS

Purity: >98.0%(GC)

Color and Shape: White to Orange to Green powder to lump

Molecular weight: 204.07

Ref: 3B-D4912

2,4-Dichlorophenyl isothiocyanate

CAS: 6590-96-1

Formula: C₇H₃Cl₂NS

Purity: 98%

Color and Shape: Solid

Molecular weight: 204.07

Ref: 10-F008792

2,4-Dichlorophenyl isothiocyanate

CAS: 6590-96-1

2,4-Dichlorophenyl isothiocyanate (2,4-DCPI) is a benzimidazole derivative that binds to the benzimidazole-binding site of the α1 subunit of the glutamate receptor. 2,4-DCPI inhibits tumor cell proliferation by binding to a specific region of the alpha 1 subunit of the glutamate receptor. This binding prevents glutamate from activating its receptor and initiating intracellular signaling pathways that promote tumor cell growth. 2,4-DCPI has been shown to inhibit the proliferation of human cancer cells in culture with significant inhibitory activities against mda-mb231 cells. It also inhibits angiogenesis and metastasis by inhibiting vascular endothelial growth factor (VEGF) production. The molecule was observed to have an effect on chloride secretion in rats, which may be related to its pharmacokinetic properties.

Formula: C₇H₃Cl₂NS

Purity: Min. 95%

Molecular weight: 204.08 g/mol

Ref: 3D-GAA59096