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CAS 659729-09-6

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4-chloro-6-[4-(trifluoromethyl)phenyl]pyrimidine

Description:
4-Chloro-6-[4-(trifluoromethyl)phenyl]pyrimidine is a heterocyclic organic compound characterized by a pyrimidine ring substituted with a chlorine atom and a para-trifluoromethylphenyl group. The presence of the chlorine atom at the 4-position and the trifluoromethyl group at the 6-position contributes to its unique chemical properties, including increased lipophilicity and potential biological activity. This compound is often studied for its applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its ability to interact with biological targets. The trifluoromethyl group enhances the compound's metabolic stability and can influence its binding affinity to proteins. Additionally, the compound may exhibit interesting electronic properties due to the electron-withdrawing nature of the trifluoromethyl group, which can affect its reactivity and interactions in various chemical environments. Overall, 4-chloro-6-[4-(trifluoromethyl)phenyl]pyrimidine is a valuable compound in research and development, particularly in the fields of drug discovery and agrochemicals.
Formula:C11H6ClF3N2
InChI:InChI=1/C11H6ClF3N2/c12-10-5-9(16-6-17-10)7-1-3-8(4-2-7)11(13,14)15/h1-6H
SMILES:c1cc(ccc1c1cc(Cl)ncn1)C(F)(F)F
Synonyms:
  • Pyrimidine, 4-Chloro-6-[4-(Trifluoromethyl)Phenyl]-
  • 4-Chloro-6-[4-(trifluoromethyl)phenyl]pyrimidine
  • 4-Chloro-6-(4'-(trifluoromethyl)phenyl)pyrimidine
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