CAS 659742-21-9

6-Methylpyridine-3-boronic acid

Description:

6-Methylpyridine-3-boronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a pyridine ring. This compound features a methyl group at the 6-position of the pyridine, which contributes to its unique reactivity and solubility properties. It is typically a white to off-white solid and is soluble in polar solvents such as water and alcohols, making it useful in various chemical reactions. The boronic acid group allows for participation in Suzuki coupling reactions, which are essential in the synthesis of biaryl compounds and pharmaceuticals. Additionally, 6-Methylpyridine-3-boronic acid can act as a ligand in coordination chemistry and is utilized in the development of sensors and in medicinal chemistry for drug design. Its reactivity can be influenced by the presence of the methyl group, which can affect sterics and electronic properties. As with many boronic acids, it is important to handle this compound with care, as it can be sensitive to moisture and air.

Formula: C₆H₈BNO₂

InChI: InChI=1/C6H8BNO2/c1-5-2-3-6(4-8-5)7(9)10/h2-4,9-10H,1H3

SMILES: Cc1ccc(cn1)B(O)O

Synonyms:

• 2-Picoline-5-boronic acid
• (6-Methyl-3-Pyridyl)Boronic Acid
• 2-Methyl-5-Pyridinylboronic Acid
• 2-Methylpyridine-5-Boronic Acid

(6-Methylpyridin-3-yl)boronic acid

CAS: 659742-21-9

Formula: C₆H₈BNO₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 136.9442

Ref: IN-DA003HW5

6-Methylpyridine-3-boronic acid

CAS: 659742-21-9

6-Methylpyridine-3-boronic acid

Formula: C₆H₈BNO₂

Purity: ≥95%

Color and Shape: white solid

Molecular weight: 136.94g/mol

Ref: 54-OR11980

2-Methylpyridine-5-boronic acid

CAS: 659742-21-9

Formula: C₆H₈BNO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 136.95

Ref: 10-F049855

6-Methylpyridine-3-boronic Acid Hydrochloride Hydrate

Controlled Product

CAS: 659742-21-9

Stability Hygroscopic
Applications 6-Methylpyridine-3-boronic Acid Hydrochloride Hydrate is the Hydrochloride of M326565, which is used in the preparation of various biologically active compound such as phosphoinositide-3-kinases (PI3K) and c-jun N-terminal kinase (JNK) inhibitors.
References Smith, A.L. et al.: J. Med. Chem., 55, 5188 (2012); Perry, B. et al.: Bioorg. Med. Chem. Lett., 18, 4700 (2008); Chambers, J. et al.: ACS Chem. Neurosci., 2, 198 (2011);

Formula: C₆H₈BNO₂·HCl·xH₂O

Color and Shape: Neat

Molecular weight: 136.94+36.46+x(18.02)

Ref: TR-M327090