CAS 65996-58-9

2-amino-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one

Description:

2-amino-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, with the CAS number 65996-58-9, is a heterocyclic organic compound characterized by its unique bicyclic structure that incorporates both pyrrole and pyrimidine moieties. This compound typically exhibits a range of biological activities, making it of interest in medicinal chemistry. It is often studied for its potential as a pharmacological agent, particularly in the context of cancer research and other therapeutic applications. The presence of amino and carbonyl functional groups contributes to its reactivity and solubility in various solvents. Additionally, the compound's structural features may influence its interaction with biological targets, such as enzymes or receptors. Its stability and reactivity can vary depending on environmental conditions, including pH and temperature. Overall, 2-amino-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one represents a significant class of compounds with potential applications in drug development and biochemistry.

Formula: C₆H₆N₄O

InChI: InChI=1/C6H6N4O/c7-6-9-3-1-2-8-4(3)5(11)10-6/h1-2,8H,(H3,7,9,10,11)

SMILES: c1c[nH]c2c1[nH]c(=N)nc2O

Synonyms:

• 2-Amino-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
• 2-amino-5H-pyrrolo[3,2-d]pyrimidin-4-ol
• 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-3,5-dihydro-
• 5H-pyrrolo[3,2-d]pyrimidin-4-ol, 2-amino-
• 2-Amino-3,5-Dihydro-Pyrrolo[3,2-D]Pyrimidin-4-One

4H-​Pyrrolo[3,​2-​d]​pyrimidin-​4-​one, 2-​amino-​3,​5-​dihydro-

CAS: 65996-58-9

Formula: C₆H₆N₄O

Purity: 96%

Color and Shape: Solid

Molecular weight: 150.1380

Ref: IN-DA00FAXP

9-Deazaguanine

CAS: 65996-58-9

9-Deazaguanine

Purity: 96%

Ref: 54-OR1040968

9-Deazaguanine

CAS: 65996-58-9

9-Deazaguanine is an analog of guanine, which has inhibitory properties. It reacts with the hydrogen bond of the enzyme and prevents its reaction with a substrate. 9-Deazaguanine binds to the target enzymes trifluoroacetic acid (TFA) and hydrogen bond interactions with water molecules. The reaction mechanism is based on the competitive inhibition of TFA, which is an important enzyme in DNA synthesis. 9-Deazaguanine inhibits the growth of k562 cells by inhibiting protein synthesis at specific sites in the ribosome. 9-Deazaguanine also shows inhibitory properties against autoimmune diseases and infectious diseases because it inhibits immune system reactions that are mediated by antibodies and T cells.

Formula: C₆H₆N₄O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 150.14 g/mol

Ref: 3D-FD09249

2-Amino-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one

CAS: 65996-58-9

Formula: C₆H₆N₄O

Purity: 96%

Color and Shape: Solid

Molecular weight: 150.141

Ref: 10-F036697

9-Deazaguanine

Controlled Product

CAS: 65996-58-9

Applications A nucleoside analog as potent inhibitor of purine nucleoside phosphorylase.
References Erion, M.D., et al.: J. Med. Chem., 36, 3771 (1993), Seela, F., et al.: Org. Biomol. Chem., 4, 3993 (2006), Hikishima S., et al.: Bioorg. Med. Chem. Lett., 17, 4173 (2007),

Formula: C₆H₆N₄O

Color and Shape: Neat

Molecular weight: 150.14

Ref: TR-D201330

9-Deazaguanine

CAS: 65996-58-9

9-Deazaguanine is a nucleoside analogue exhibiting inhibitory activity against bovine purine nucleoside phosphorylase (PNP).

Formula: C₆H₆N₄O

Purity: 98%

Color and Shape: Solid

Molecular weight: 150.14

Ref: TM-T78379