CAS 66-02-4

3,5-Diiodotyrosine

Description:

3,5-Diiodotyrosine is an iodinated derivative of the amino acid tyrosine, characterized by the presence of two iodine atoms attached to the aromatic ring at the 3 and 5 positions. This compound is typically a white to off-white solid and is soluble in organic solvents but has limited solubility in water. It plays a significant role in the biosynthesis of thyroid hormones, particularly thyroxine (T4), as it is an intermediate in the iodination process that occurs in the thyroid gland. The presence of iodine in its structure enhances its biological activity and is crucial for the proper functioning of the thyroid. 3,5-Diiodotyrosine can also be used in biochemical research and studies related to thyroid function and disorders. Its molecular formula is C9H8I2N1O3, and it has a relatively low molecular weight. As with many iodinated compounds, it is important to handle 3,5-diiodotyrosine with care due to potential biological effects and the need for proper disposal methods.

Formula: C₉H₉I₂NO₃

InChI: InChI=1S/C9H9I2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)

InChI key: InChIKey=NYPYHUZRZVSYKL-UHFFFAOYSA-N

SMILES: C(C(C(O)=O)N)C1=CC(I)=C(O)C(I)=C1

Synonyms:

• 2-Amino-3-(4-hydroxy-3,5-diiodo-phenyl)-propionic acid
• 2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
• 2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoicacid
• 3,5-Di-Iodo Tyrosine
• 3,5-Diiodo-4-hydroxyphenylalanine
• 3,5-Diiodo-<span class="text-smallcaps">D</smallcap><smallcap>L</span>-tyrosine
• 3,5-Diiodotyrocine
• 3,5-Diiodotyrosine
• 4-Hydroxy-3,5-diiodophenylalanine
• <span class="text-smallcaps">DL</span>-3,5-Diiodotyrosine
• Agontan
• Apothyrin
• Cemiod
• Dityrin
• Flaianina
• Gorgoic acid, diiodo-
• Gorgonic acid, diiodo-
• Iodogorgoic acid
• Iodogorgonic acid
• Jodgorgon
• NSC 208959
• NSC 97936
• Tyrosine, 3,5-diiodo-
• β-(4-Hydroxy-3,5-diiodophenyl)alanine

Diidotyrosine

CAS: 66-02-4

Formula: C₉H₉I₂NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 432.9816

Ref: IN-DA00IBJP

2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid

CAS: 66-02-4

2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid

Purity: 95%

Molecular weight: 432.98g/mol

Ref: 54-OR27970

3,5-Diiodo-DL-tyrosine

Controlled Product

CAS: 66-02-4

Applications 3,5-Diiodo-DL-tyrosine is used for diagnosis of hypothyroidism caused by DEHAL1 gene defects.
References Encinas, S., et al.: Chem. Res. Toxicol., 11, 946 (1998), Daneshvar, A., et al.: Chemosphere, 80, 301 (2010), Eriksson, J., et al.: Photochem. Photobiol., 86, 528 (2010),

Formula: C₉H₉I₂NO₃

Color and Shape: Neat

Molecular weight: 432.98

Ref: TR-D455175

2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid

CAS: 66-02-4

Purity: 95%

Molecular weight: 432.9840088

Ref: 10-F602167