CAS 66-75-1

Uracil mustard

Description:

Uracil mustard, with the CAS number 66-75-1, is a synthetic compound that is a derivative of uracil, a nucleobase found in RNA. It is classified as an alkylating agent, which means it can form covalent bonds with DNA, leading to potential therapeutic applications in cancer treatment. Uracil mustard is known for its ability to interfere with DNA replication and transcription, making it a candidate for use in chemotherapy. The compound exhibits characteristics typical of alkylating agents, including the potential for cytotoxicity and mutagenicity. Its structure includes a mustard group, which contributes to its reactivity. Uracil mustard is soluble in water and exhibits moderate stability under physiological conditions. However, it can undergo hydrolysis, which may affect its efficacy and stability in biological systems. Due to its mechanism of action, uracil mustard has been studied for its potential to target rapidly dividing cells, although its clinical use may be limited by side effects and resistance mechanisms in cancer cells.

Formula: C₈H₁₁Cl₂N₃O₂

InChI: InChI=1S/C8H11Cl2N3O2/c9-1-3-13(4-2-10)6-5-11-8(15)12-7(6)14/h5H,1-4H2,(H2,11,12,14,15)

InChI key: InChIKey=IDPUKCWIGUEADI-UHFFFAOYSA-N

SMILES: N(CCCl)(CCCl)C=1C(=O)NC(=O)NC1

Synonyms:

• 2,4-(1H,3H)-Pyrimidinedione, 5-[bis(2-chloroethyl)amino]-
• 2,6-Dihydroxy-5-bis[2-chloroethyl]aminopyrimidine
• 5-N,N-bis(2-chloroethyl)aminouracil
• 5-[Bis(2-chloroethyl)amino]uracil
• 5-[Di(beta-chloroethyl)amino]uracil
• 5-[Di(β-chloroethyl)amino]uracil
• 5-[bis(2-chloroethyl)amino]-2,4-(1H,3H)-Pyrimidinedione
• Aminouracil mustard
• Cb-4835
• Chlorethaminacil
• Demethyldopan
• Desmethyldopan
• Ent 50439
• Nci C04820
• Nordopan
• Nsc-34462
• Sk-19849
• U-8344
• Uracil mustard
• Uracil nitrogen mustard
• Uracil, 5-[bis(2-chloroethyl)amino]-
• Uracillost
• Uracilmostaza
• Uramustin
• Uramustina

5-[Bis(2-chloroethyl)amino]pyrimidine-2,4-diol

Controlled Product

CAS: 66-75-1

Applications 5-[bis(2-chloroethyl)amino]pyrimidine-2,4-diol (cas# 66-75-1) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Formula: C₈H₁₁Cl₂N₃O₂

Color and Shape: Neat

Molecular weight: 252.1

Ref: TR-B416270