CAS 66-86-4

Neomycin C

Description:

Neomycin C, with the CAS number 66-86-4, is an aminoglycoside antibiotic that is primarily derived from the bacterium Streptomyces fradiae. It is known for its broad-spectrum antibacterial activity, particularly against Gram-negative bacteria, and is often used in topical formulations to treat infections. Neomycin C is characterized by its complex structure, which includes multiple amino sugars linked by glycosidic bonds, contributing to its mechanism of action that inhibits bacterial protein synthesis. This compound is typically administered topically or via injection, as it is poorly absorbed from the gastrointestinal tract. Neomycin C can cause side effects, including nephrotoxicity and ototoxicity, particularly with systemic use. Its solubility in water makes it suitable for various pharmaceutical applications, but it is important to monitor for potential allergic reactions in sensitive individuals. Overall, Neomycin C remains a valuable antibiotic in clinical settings, particularly for localized infections.

Formula: C₂₃H₄₆N₆O₁₃

InChI: InChI=1/C23H46N6O13.ClH/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;/h5-23,30-36H,1-4,24-29H2;1H/t5-,6+,7-,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1

InChI key: InChIKey=PGBHMTALBVVCIT-VZXHOKRSSA-N

SMILES: O([C@H]1[C@H](O[C@H]2[C@H](O)[C@H](O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@@H](CO)O2)[C@@H](O)[C@H](N)C[C@@H]1N)[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N

Synonyms:

• Neomycin C
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-
• O-2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-
• Dekamycin II
• Neomycin EP Impurity
• Framycetin Impurity 3 (Framycetin EP Impurity C)
• 4-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-[3-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-β-D-ribofuranosyl]-2-deoxy-D-streptamine
• Framycetin EP Impurity C
• Framycetin sulfate EP Impurity C
• 5-amino-2-(aminomethyl)-6-[5-[3,5-diamino-2-[3-amino-6-(aminomethyl)-4 ,5-dihydroxy-oxan-2-yl]oxy-6-hydroxy-cyclohexyl]oxy-4-hydroxy-2-(hydro xymethyl)oxolan-3-yl]oxy-oxane-3,4-diol
• Neomycin C sulfate
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-, monohydrochloride (9CI)

Neomycin EP Impurity C (Neomycin C)

CAS: 66-86-4

Formula: C₂₃H₄₆N₆O₁₃

Color and Shape: Off-White Solid

Molecular weight: 614.65

Ref: 4Z-N-080016

Neomycin C

CAS: 66-86-4

Neomycin C, less potent isomer of Neomycin complex, is part of a 2-DOS aminoglycoside.

Formula: C₂₃H₄₆N₆O₁₃

Color and Shape: Solid

Molecular weight: 614.64

Ref: TM-T73953

Neomycin EP Impurity C (Neomycin C) TFA Salt

CAS: 66-86-4

Formula: C₂₃H₄₆N₆O₁₃·xC₂HF₃O₂

Color and Shape: Off-White Solid

Molecular weight: 614.65 x*114.02

Ref: 4Z-N-080005

Neomycin C Hexaacetate

CAS: 66-86-4

Stability Hygroscopic
Applications Neomycin C Hexaacetate is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.
References Umezawa, S., et al.: Bull. Chem. Soc. Jpm., 53, 3259 (1980); The Journal of antibiotics, NO. 2. 189 (1977);

Formula: C₂₃H₄₆N₆O₁₃•6(CH₃COOH)

Color and Shape: Neat

Molecular weight: 614.6466005

Ref: TR-N389980

Neomycin EP impurity C (Neomycin C) trifluoroacetate

CAS: 66-86-4

Neomycin EP impurity C (Neomycin C) trifluoroacetate is a reference standard, which is a meticulously characterized chemical impurity often used in pharmaceutical analysis. This compound is derived from the fermentation of *Streptomyces fradiae*, which produces a complex mixture of aminoglycoside antibiotics, including Neomycin B and Neomycin C.

Formula: C₂₃H₄₆N₆O₁₃•(C₂HF₃O₂)x

Purity: Min. 95%

Ref: 3D-AN183301

Neomycin C hexaacetate

CAS: 66-86-4

Please enquire for more information about Neomycin C hexaacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₃H₄₆N₆O₁₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 614.6 g/mol

Ref: 3D-AAA06686

Neomycin sulfate EP Impurity C

CAS: 66-86-4

Formula: C₂₃H₄₆N₆O₁₃

Molecular weight: 614.65

Ref: ST-EA-CP-N53003