CAS 66016-70-4

6,6-dimethyl-5-(8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl)-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium bromide

Description:

6,6-Dimethyl-5-(8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl)-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-6-ium bromide, with CAS number 66016-70-4, is a complex organic compound characterized by its intricate molecular structure, which includes multiple fused rings and functional groups. This substance features a quaternary ammonium structure, indicated by the "ium" suffix, suggesting it carries a positive charge. The presence of bromide as a counterion is typical for quaternary ammonium compounds, enhancing solubility in polar solvents. The compound's structure incorporates both dioxole and isoquinoline moieties, which may contribute to its potential biological activity. Such compounds often exhibit interesting pharmacological properties, including antimicrobial or anticancer activities, although specific biological data for this compound may not be widely available. Its synthesis and characterization would typically involve advanced organic chemistry techniques, and its stability, solubility, and reactivity would depend on the specific conditions under which it is handled.

Formula: C₂₁H₂₀NO₆·Br

InChI: InChI=1/C21H20NO6.BrH/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19;/h3-4,7-8,18-19H,5-6,9-10H2,1-2H3;1H/q+1;/p-1

Synonyms:

• (6R)-6-[(5S)-6,6-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one
• (5S)-5-[(6R)-6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium bromide (1:1)
• 1(s),9(r)-(-)-bicuculline methobromide
• (-)-BICUCULLINE METHBROMIDE
• 1(S),9(R)-(-)-Bicuculline methbromide
• [r-(r*,s*)]-5-(6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquindinium bromide

1(S);9(R)-(-)-Bicuculline methbromide

CAS: 66016-70-4

Formula: C₂₁H₂₀BrNO₆

Molecular weight: 462.29

Ref: 7W-GL4442

1(S),9(R)-(-)-Bicuculline methbromide

CAS: 66016-70-4

1(S),9(R)-(-)-Bicuculline methbromide is a potent inhibitor of protein kinases that has been shown to induce apoptosis in cancer cells. It is derived from the urine of Chinese strain rats and inhibits the activity of D-xylose kinase, which is involved in the metabolism of xylose. 1(S),9(R)-(-)-Bicuculline methbromide has been studied extensively for its anti-cancer properties and has shown promising results in tumor cell lines. It induces apoptosis in human cancer cells by inhibiting the activity of specific kinases that are essential for cell survival. This compound may be a potential candidate for cancer therapy due to its ability to selectively target cancer cells while sparing normal cells.

Formula: C₂₁H₂₀BrNO₆

Purity: Min. 95%

Molecular weight: 462.3 g/mol

Ref: 3D-RCA01670

Bicuculline methobromide

CAS: 66016-70-4

Bicuculline methobromide: GABAA antagonist, IC50=3μM, induces convulsions, used in epilepsy research.

Formula: C₂₁H₂₀BrNO₆

Color and Shape: Solid

Molecular weight: 462.29

Ref: TM-T72246