CAS 66018-38-0

(3S,5Z,8S,9S,11E)-3,4,9,10-Tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione

Description:

The chemical substance with the name "(3S,5Z,8S,9S,11E)-3,4,9,10-Tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione" and CAS number "66018-38-0" is a complex organic compound characterized by its unique stereochemistry and functional groups. It features multiple hydroxyl (-OH) groups, which contribute to its potential solubility in polar solvents and may influence its biological activity. The presence of a methoxy (-OCH3) group suggests possible interactions in biological systems, enhancing its reactivity and potential as a pharmacophore. The compound's structure includes a benzoxacyclotetradecine framework, indicating it may exhibit interesting conformational properties and reactivity patterns. Its stereochemical configuration, denoted by the specific (S) and (Z) designations, implies that it may have distinct optical isomers, which can lead to varying biological effects. Overall, this compound's intricate structure and functional groups suggest potential applications in medicinal chemistry, particularly in the development of therapeutic agents.

Formula: C₁₉H₂₂O₇

InChI: InChI=1S/C19H22O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h3-4,6-7,9-11,15,18,21-23H,5,8H2,1-2H3/b6-4+,7-3-/t11-,15-,18+/m0/s1

InChI key: InChIKey=NEQZWEXWOFPKOT-BYRRXHGESA-N

SMILES: OC1=C2C(=CC(OC)=C1)/C=C/C[C@H](O)[C@H](O)C(=O)/C=C\C[C@H](C)OC2=O

Synonyms:

• 1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,9,10-tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-, (3S,5Z,8S,9S,11E)-
• LL-Z 1640-2
• F 152
• L 783279
• (3S,5Z,8S,9S,11E)-3,4,9,10-Tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione

5Z-7-Oxozeaenol

CAS: 66018-38-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₉H₂₂O₇

Color and Shape: White to pale cream, Powder

Molecular weight: 362.37

Ref: 02-J66651

LL-Z-1640-2

CAS: 66018-38-0

Formula: C₁₉H₂₂O₇

Purity: 98.92%

Molecular weight: 362.0

Ref: 8R-AD0008

Antibiotic LL Z1640-2

CAS: 66018-38-0

Antibiotic LL Z1640-2 is an inhibitor against the TAK1 activity.

Formula: C₁₉H₂₂O₇

Color and Shape: Solid

Molecular weight: 362.38

Ref: TM-T68914

(5Z)-7-Oxozeaenol

CAS: 66018-38-0

(5Z)-7-Oxozeaenol is a natural product that inhibits the transcription factor nuclear factor kappa B (NF-κB) by binding to toll-like receptor 4. It has been shown to inhibit the growth of mesenchymal cells, leading to an increase in markers for epithelial mesenchymal transition. (5Z)-7-Oxozeaenol also induces apoptosis in breast cancer cells, specifically MDA-MB-231 cells. It activates protein kinase A and inhibits protein kinase C. This compound also inhibits the production of vasoactive intestinal peptide and TNF-α. The inhibition of these proteins leads to a decrease in cell growth and proliferation.

Formula: C₁₉H₂₂O₇

Purity: Min. 95%

Molecular weight: 362.37 g/mol

Ref: 3D-FO177760