CAS 66054-36-2

2,4(1H,3H)-Pyrimidinedione,1-[(11S)-11-O-[2-(acetylamino)-2-deoxy-a-D-glucopyranosyl]-6,10-dideoxy-10-[[(2E)-13-methyl-1-oxo-2-tetradecenyl]amino]-L-galacto-b-D-allo-undecodialdo-1,4-furanose-11,7-pyranos-1-yl]-

Description:

2,4(1H,3H)-Pyrimidinedione, with the CAS number 66054-36-2, is a complex organic compound characterized by its unique structural features, including a pyrimidinedione core and a glycosylated side chain. This substance is notable for its potential biological activity, often studied in the context of medicinal chemistry and drug development. The presence of multiple functional groups, such as acetylamino and dideoxy sugars, suggests that it may interact with various biological targets, potentially influencing metabolic pathways. Its molecular structure indicates a degree of stereochemistry, which can affect its reactivity and interactions with enzymes or receptors. Additionally, the compound's solubility, stability, and bioavailability are critical factors that influence its pharmacological properties. Overall, 2,4(1H,3H)-Pyrimidinedione represents a class of compounds that may have significant implications in therapeutic applications, particularly in the fields of antiviral or anticancer research, although specific studies would be necessary to elucidate its full potential and mechanisms of action.

Formula: C₃₈H₆₂N₄O₁₆

Synonyms:

• Tunicamycin B1
• (+)-Tunicamycin V
• 2,4(1H,3H)-Pyrimidinedione,1-[[10(E),11S]-11-O-[2-(acetylamino)-2-deoxy-a-D-glucopyranosyl]-6,10-dideoxy-10-[(13-methyl-1-oxo-2-tetradecenyl)amino]-L-galacto-b-D-allo-undecodialdo-1,4-furanose-11,7-pyranos-1-yl]-
• Tunicamycin A
• Tunicamycin V

Tunicamycin V

CAS: 66054-36-2

Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contains a 15-carbon N-acyl chain with variable branching patterns.

Formula: C₃₈H₆₂N₄O₁₆

Color and Shape: Solid

Molecular weight: 830.926

Ref: TM-T38299

Tunicamycin V

CAS: 66054-36-2

Tunicamycin V is an antibiotic and nucleoside analog, which is a secondary metabolite derived from various Streptomyces species. It functions predominantly by inhibiting the initial step of N-linked glycosylation, a critical post-translational modification process in eukaryotic cells. This inhibition occurs through the blockage of UDP-N-acetylglucosamine: dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase, thereby preventing the synthesis of dolichol-linked oligosaccharides and ultimately affecting protein folding and quality control mechanisms within the endoplasmic reticulum.

Formula: C₃₈H₆₂N₄O₁₆

Purity: Min. 95%

Molecular weight: 830.9 g/mol

Ref: 3D-RCA05436