CAS 66081-36-5
:tunicamycin C1 homolog
Description:
Tunicamycin C1 homolog, with the CAS number 66081-36-5, is a glycosylation inhibitor that belongs to the class of nucleoside antibiotics. It is primarily derived from the bacterium Streptomyces lysosuperificus. This compound is characterized by its ability to inhibit N-linked glycosylation, which is a critical post-translational modification of proteins. Tunicamycin C1 homolog exhibits a complex structure that includes a nucleoside moiety linked to an amino sugar, contributing to its biological activity. It has been studied for its potential applications in cancer research and as a tool in cell biology to understand glycoprotein synthesis. The compound is known for its cytotoxic effects on certain cell lines, making it a subject of interest in pharmacological studies. Additionally, tunicamycin C1 homolog's mechanism of action involves the inhibition of the enzyme UDP-N-acetylglucosamine: dolichyl-phosphate N-acetylglucosaminephosphotransferase, which is essential for the initial steps of glycoprotein biosynthesis.
Formula:C39H64N4O16
InChI:InChI=1/C39H64N4O16/c1-20(2)14-12-10-8-6-4-5-7-9-11-13-15-25(47)41-28-32(52)29(49)23(56-38(28)59-37-27(40-21(3)45)31(51)30(50)24(19-44)57-37)18-22(46)35-33(53)34(54)36(58-35)43-17-16-26(48)42-39(43)55/h13,15-17,20,22-24,27-38,44,46,49-54H,4-12,14,18-19H2,1-3H3,(H,40,45)(H,41,47)(H,42,48,55)/b15-13-/t22?,23-,24+,27+,28-,29+,30+,31+,32-,33+,34-,35?,36-,37+,38+/m1/s1
Synonyms:- tunicamycin B complex
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
Tunicamycin VII
CAS:<p>Tunicamycin VII is a useful organic compound for research related to life sciences. The catalog number is T124449 and the CAS number is 66081-36-5.</p>Formula:C39H64N4O16Color and Shape:SolidMolecular weight:844.953Tunicamycin vii
CAS:<p>Tunicamycin VII is an inhibitor that has been shown to induce apoptosis in human cells by inhibiting kinases. It has also been found to have anticancer properties, as it inhibits the growth of tumor cells. Tunicamycin VII has been used in Chinese hamster ovary cells to study the effects of quetiapine on cell growth and apoptosis. It is also used as a research tool in studies of somatostatin analog inhibitors for cancer treatment. Tunicamycin VII is excreted primarily in urine and may be useful as a biomarker for monitoring the efficacy of anticancer therapies.</p>Formula:C39H64N4O16Purity:Min. 95%Molecular weight:844.9 g/mol

