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CAS 660846-80-0

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Fmoc-Arg(Pbf)-Gly-OH

Description:
Fmoc-Arg(Pbf)-Gly-OH is a protected peptide derivative commonly used in peptide synthesis. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino terminus, allowing for selective coupling reactions without interfering with the peptide's functionality. The "Arg" refers to arginine, an amino acid characterized by its positively charged side chain at physiological pH, which plays a crucial role in protein interactions and stability. The "(Pbf)" indicates the presence of a 2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl (Pbf) protecting group on the arginine side chain, which helps to protect the guanidinium group during synthesis. "Gly" denotes glycine, the simplest amino acid, contributing flexibility to the peptide structure. The "OH" at the end signifies that the molecule is in its free acid form. Overall, Fmoc-Arg(Pbf)-Gly-OH is utilized in solid-phase peptide synthesis and is valued for its stability and ease of handling, making it a key intermediate in the production of various peptides and therapeutic compounds.
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