CAS 66085-59-4: Nimodipine

Description:Nimodipine is a dihydropyridine calcium channel blocker primarily used in the medical field for its ability to improve cerebral blood flow. It is particularly indicated for the prevention of ischemic neurological deficits following subarachnoid hemorrhage. The compound is characterized by its selective action on cerebral blood vessels, leading to vasodilation without significantly affecting systemic blood pressure. Nimodipine has a relatively high lipophilicity, which facilitates its penetration across the blood-brain barrier. Its chemical structure includes a 1,4-dihydropyridine ring, which is essential for its pharmacological activity. The substance is typically administered orally or intravenously, and its pharmacokinetics involve rapid absorption and metabolism, with a relatively short half-life. Common side effects may include headache, hypotension, and gastrointestinal disturbances. Due to its specific action and side effect profile, nimodipine is a valuable therapeutic agent in neurology, particularly in managing conditions related to cerebral vasospasm.

Formula:C₂₁H₂₆N₂O₇

InChI:InChI=1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3

InChI key:InChIKey=UIAGMCDKSXEBJQ-UHFFFAOYSA-N

SMILES:O=C(OCCOC)C1=C(NC(=C(C(=O)OC(C)C)C1C=2C=CC=C(C2)N(=O)=O)C)C

Synonyms:
1,4-Dihydro-2,6-Dimethyl-4-(3-Nitrophenyl)-3,5-Pyridinedicarboxylic Acid 2-Methoxyethyl 1-Methylethyl Ester
2-Methoxyethyl Propan-2-Yl 2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3,5-Dicarboxylate
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-methoxyethyl 1-methylethyl ester
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(2-methoxyethyl) 5-(1-methylethyl) ester
3-(2-methoxyethyl) 5-(1-methylethyl) (4R)-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydropyridine-3,5-dicarboxylate
3-(2-methoxyethyl) 5-(1-methylethyl) (4S)-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydropyridine-3,5-dicarboxylate
3-O-(2-Methoxyethyl) 5-O-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Admon
BAY-e 9736
Isopropyl 2-Methoxyethyl 1,4-Dihydro-2,6-Dimethyl-4-(M-Nitrophenyl)-3,5-Pyridinedicarboxylate
See more synonyms
Nemotan
Nimodipin
Nimodipine AP
Nimodipino
Nimotop
Periplum
Nimodipine

Found 17 products.

Product data	Purity	Price range	Estimated delivery
Nimodipine, 98+% REF: 02-J61287CAS: 66085-59-4	98+%	To inquire	Fri 11 Apr 25
Nimodipine CRS REF: 41-N0850000CAS: 66085-59-4	- - -	115.00 €	Tue 15 Apr 25
Nimodipine REF: 47-651CAS: 66085-59-4	100.0%	242.00 €	Tue 15 Apr 25
Nimodipine REF: 45-1463858CAS: 66085-59-4	- - -	463.00 €	Wed 16 Apr 25
Nimodipine REF: TM-T0343CAS: 66085-59-4	99.64% - 99.79%	48.00 €~79.00 €	Thu 17 Apr 25
Nimodipine REF: 54-OR1030244CAS: 66085-59-4	- - -	32.00 €~676.00 €	Mon 21 Apr 25
Nimodipine REF: 7W-GP2955CAS: 66085-59-4	≥ 98.0% (anhydrous basis)	58.00 €	Mon 21 Apr 25
Nimodipine REF: 54-BUP14874CAS: 66085-59-4	99.7%	69.00 €~488.00 €	Mon 21 Apr 25
Nimodipine REF: 4Z-N-151CAS: 66085-59-4	- - -	To inquire	Mon 21 Apr 25
Nimodipine REF: 3B-N0896CAS: 66085-59-4	>98.0%(HPLC)	75.00 €~235.00 €	Tue 22 Apr 25
Nimodipine 100 µg/mL in Acetonitrile REF: 04-A15526800AL-100CAS: 66085-59-4	- - -	73.00 €	Tue 22 Apr 25
Nimodipine REF: 04-C15526800CAS: 66085-59-4	- - -	118.00 €	Tue 22 Apr 25
Nimodipine REF: 86-MM0416.00CAS: 66085-59-4	- - -	736.00 €	Tue 22 Apr 25
Nimodipine REF: AC-32928CAS: 66085-59-4	- - -	To inquire	Tue 22 Apr 25
Nimodipine REF: TR-N478200CAS: 66085-59-4	- - -	101.00 €~791.00 €	Tue 29 Apr 25
Nimodipine REF: 10-M02160CAS: 66085-59-4	>98%	To inquire	Tue 29 Apr 25
Nimodipine REF: 3D-II57946CAS: 66085-59-4	Min. 98 Area-%	202.00 €~877.00 €	Mon 28 Apr 25