CAS 66104-22-1

Pergolide

Description:

Pergolide is a synthetic ergot derivative primarily used as a medication for the treatment of Parkinson's disease and certain conditions related to hyperprolactinemia. It acts as a dopamine receptor agonist, specifically targeting D2 and D1 receptors, which helps to alleviate symptoms associated with dopamine deficiency. Pergolide is characterized by its complex chemical structure, which includes a bicyclic core typical of ergot alkaloids. The substance is typically administered orally and has a relatively long half-life, allowing for once-daily dosing in some cases. Its pharmacokinetics can be influenced by factors such as liver metabolism and individual patient characteristics. While effective, pergolide has been associated with potential side effects, including nausea, hallucinations, and cardiovascular complications, leading to its withdrawal from the market in some regions. As with any medication, careful monitoring and dosage adjustments are essential to optimize therapeutic outcomes while minimizing adverse effects.

Formula: C₁₉H₂₆N₂S

InChI: InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1

InChI key: InChIKey=YEHCICAEULNIGD-MZMPZRCHSA-N

SMILES: C(CC)N1[C@]2([C@@](C=3C=4C(C2)=CNC4C=CC3)(C[C@@H](CSC)C1)[H])[H]

Synonyms:

• (8β)-8-[(Methylthio)methyl]-6-propylergoline
• 8-β-[(Methylthio)methyl]-6-(propionyl)ergoline
• <span class="text-smallcaps">D</span>-8β-[(Methylthio)methyl]-6-propylergoline
• D-8β-[(Methylthio)methyl]-6-propylergoline
• Indolo[4,3-fg]quinoline, ergoline deriv.
• Ly 141B
• Pergolide
• (6aR,9R,10aR)-9-[(methylsulfanyl)methyl]-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline
• D-6-n-Propyl-8b-methylmercaptomethylergoline
• (8beta)-8-[(methylsulfanyl)methyl]-6-propylergoline methanesulfonate (1:1)
• (6aR,9R,10aR)-9-(Methylthiomethyl)-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline
• Ergoline, 8-((methylthio)methyl)-6-propyl-, (8beta)-
• 8.beta.-[(Methylthio)methyl]-6-propylergoline
• Ergoline, 8-[(methylthio)methyl]-6-propyl-, (8β)-
• (8beta)-8-[(Methylsulfanyl)methyl]-6-propylergoline
• (8beta)-8-[(methylthio)methyl]-6-propylergoline
• (6aR,9R,10aR)-9-[(Methylsulfanyl)methyl]-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]chinolin

(2R,4R,7R)-4-[(methylsulfanyl)methyl]-6-propyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(15),9,12(16),13-tetraene

CAS: 66104-22-1

Formula: C₁₉H₂₆N₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 314.4881

Ref: IN-DA00FA9C

Pergolide

CAS: 66104-22-1

Pergolide

Purity: ≥98%

Molecular weight: 314.49g/mol

Ref: 54-BUP21439

Pergolide

CAS: 66104-22-1

Formula: C₁₉H₂₆N₂S

Molecular weight: 314.49

Ref: 7W-GP1829

Pergolide

CAS: 66104-22-1

Formula: C₁₉H₂₆N₂S

Molecular weight: 314.49

Ref: 4Z-P-436001

Pergolide

CAS: 66104-22-1

Pergolide is a long-acting and orally active dopamine receptor D1/D2 agonist and ergoline derivative, used in the study of Parkinson's disease

Formula: C₁₉H₂₆N₂S

Purity: 99.95%

Color and Shape: Solid

Molecular weight: 314.49

Ref: TM-T21340

Pergolide

Controlled Product

CAS: 66104-22-1

D1 and D2 dopamine agonist

Formula: C₁₉H₂₆N₂S

Purity: Min. 95%

Molecular weight: 314.49 g/mol

Ref: 3D-FP162450