CAS 66104-23-2

Pergolide mesylate

Description:

Pergolide mesylate is a synthetic compound primarily used in the treatment of Parkinson's disease and certain conditions related to hyperprolactinemia. It acts as a dopamine receptor agonist, specifically targeting D2 and D1 receptors, which helps to alleviate symptoms associated with dopamine deficiency. The substance is characterized by its mesylate salt form, which enhances its solubility and bioavailability. Pergolide mesylate is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing in some cases. Its chemical structure includes a bicyclic core, which is essential for its pharmacological activity. While effective, pergolide mesylate has been associated with side effects such as nausea, dizziness, and, in some cases, more severe complications like cardiac valvulopathy. Due to safety concerns, its use has been limited, and it is often prescribed when other treatments are not suitable. Overall, pergolide mesylate exemplifies the complexities of pharmacotherapy in managing chronic neurological conditions.

Formula:C₁₉H₂₆N₂S·CH₄O₃S

InChI:InChI=1S/C19H26N2S.CH4O3S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21;1-5(2,3)4/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3;1H3,(H,2,3,4)/t13-,16-,18-;/m1./s1

InChI key:InChIKey=UWCVGPLTGZWHGS-ZORIOUSZSA-N

SMILES:C(CC)N1[C@]2([C@@](C=3C=4C(C2)=CNC4C=CC3)(C[C@@H](CSC)C1)[H])[H].S(C)(=O)(=O)O

Synonyms:

8-beta-((Methylthio)methyl)-6-propylergoline methanesulfonate
8-beta-((Methylthio)methyl)-6-propylergoline monomethane sulfonate
8beta-((Methylthio)methyl)-6-propylergoline monomethanesulfonate
Celance
Ergoline, 8-((methylthio)methyl)-6-propyl-, monomethanesulfonate, (8beta)-
Ergoline, 8-[(methylthio)methyl]-6-propyl-, (8β)-, monomethanesulfonate
Ergoline, 8-beta-((methylthio)methyl)-6-propyl-, methanesulfonate (1:1)
Indolo[4,3-fg]quinoline, ergoline deriv.
Ly 127809
Ly127809
MPE
NSC 319773
Pergolide mesylate salt
Pergolide methanesulfonate
Permax
Unii-55B9Hqy616
See more synonyms

Purity (%)

100

Found 10 products.

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PERGOLIDE MESILATE CRS
CAS:
- 66104-23-2
PERGOLIDE MESILATE CRS
Formula:C₂₀H₃₀N₂O₃S₂
Color and Shape:Powder
Molecular weight:410.5938
Ref: 41-Y0000010
150mg
115.00€
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Pergolide Mesylate
CAS:
- 66104-23-2
Alkaloids of rye ergot and their derivatives; salts thereof, nesoi
Formula:C₁₉H₂₆N₂S·CH₄O₃S
Color and Shape:White Off-White Powder
Molecular weight:314.18167
Ref: 45-1510845
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Pergolide mesylate
CAS:
- 66104-23-2
Pergolide mesylate
Purity:≥98%
Molecular weight:410.59g/mol
Ref: 54-BUP06339
5mg
76.00€
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10mg
102.00€
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25mg
178.00€
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50mg
268.00€
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Pergolide mesylate
CAS:
- 66104-23-2
Formula:C₁₉H₂₆N₂S·CH₄O₃S
Purity:≥ 98.0%
Color and Shape:White to off-white crystalline powder
Molecular weight:410.59
Ref: 7W-GP3188
ne
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Pergolide Mesilate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 66104-23-2
Formula:C₁₉H₂₆N₂S·CH₄O₃S
Color and Shape:Neat
Molecular weight:410.59
Ref: 86-MM3400.00
250mg
1,426.00€
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Pergolide mesilate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 66104-23-2
Formula:C₁₉H₂₆N₂S·CH₄O₃S
Color and Shape:Neat
Molecular weight:410.59
Ref: 04-C15989500
100mg
126.00€
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Pergolide mesylate
CAS:
- 66104-23-2
Pergolide mesylate (LY127809), a dopamine agonist for Parkinson's and hyperprolactinemia, was withdrawn for heart valve risk.
Formula:C₂₀H₃₀N₂O₃S₂
Purity:99.70%
Color and Shape:White To Off-White Solid
Molecular weight:410.59
Ref: TM-T2226
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Pergolide Mesylate-d7
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 66104-23-2
Applications A dopaminergic agonist that also decrease plasma prolactin concentrations. A labelled antiparkinsonian agent. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lemberger, L. and Crabtree, R.E.: Science, 205, 1151 (1979), Koller, W.C.: Neuropharmacology, 19, 831 (1980), Francks, S., et al.: Lancet, 2, 659 (1981), Kleinberg, D.L., et al.: N. Engl. J. Med., 309, 704 (1983) 
Formula:C₂₀H₂₃D₇N₂O₃S₂
Color and Shape:Neat
Molecular weight:417.64
Ref: TR-P287202
1mg
256.00€
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10mg
1,689.00€
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Pergolide Mesylate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 66104-23-2
Formula:C₁₉H₂₆N₂S·CH₄O₃S
Color and Shape:Neat
Molecular weight:410.59
Ref: TR-P287200
25mg
889.00€
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100mg
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2500µg
175.00€
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Pergolide mesylate
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 66104-23-2
D1 and D2 dopamine agonist
Formula:C₂₀H₃₀N₂O₃S₂
Purity:Min. 95%
Color and Shape:White To Off-White Solid
Molecular weight:410.6 g/mol
Ref: 3D-FP26840
1g
516.00€
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5g
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500mg
375.00€
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