CAS 66108-95-0

Iohexol

Description:

Iohexol is a non-ionic, water-soluble contrast agent commonly used in medical imaging, particularly in computed tomography (CT) scans and angiography. It belongs to the class of iodinated contrast media, which enhances the visibility of internal structures in radiographic imaging. Iohexol has a molecular formula that includes iodine, which is responsible for its radiopacity, allowing it to absorb X-rays effectively. The substance is characterized by its low osmolality, which reduces the risk of adverse reactions compared to older, high-osmolality contrast agents. It is typically administered intravenously and is known for its relatively low toxicity profile. Iohexol is stable under normal conditions and is excreted primarily through the kidneys, making it suitable for patients with normal renal function. However, caution is advised in individuals with renal impairment or those at risk of contrast-induced nephropathy. Overall, Iohexol is a widely used and effective agent in diagnostic imaging, facilitating clearer visualization of anatomical structures and pathological conditions.

Formula: C₁₉H₂₆I₃N₃O₉

InChI: InChI=1S/C19H26I3N3O9/c1-8(29)25(4-11(32)7-28)17-15(21)12(18(33)23-2-9(30)5-26)14(20)13(16(17)22)19(34)24-3-10(31)6-27/h9-11,26-28,30-32H,2-7H2,1H3,(H,23,33)(H,24,34)

InChI key: InChIKey=NTHXOOBQLCIOLC-UHFFFAOYSA-N

SMILES: N(CC(CO)O)(C(C)=O)C1=C(I)C(C(NCC(CO)O)=O)=C(I)C(C(NCC(CO)O)=O)=C1I

Synonyms:

• 1,3-Benzenedicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-
• 1,3-Benzenedicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N¹,N³-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-
• 5-(N-2,3-Dihydroxypropylacetamido)-2,4,6-triiodo-N,N'-bis(2,3-dihydroxypropyl)isophthalamide.
• 5-[Acetyl(2,3-dihydroxypropyl)amino]-N¹,N³-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide
• Accudenz
• Accupaque 300
• Exypaque
• Histodenz
• Iohexol
• Iopaque 240
• Iopaque 300
• Ioverin 350
• Nycodenz
• Omnipaque
• Omnipaque 140
• Omnipaque 240
• Omnipaque 300
• Omnipaque 350
• Omnipaque R
• 5-[Acetyl(2,3-dihydroxypropyl)amino]-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide

Iohexol (mixture of isomers)

CAS: 66108-95-0

Formula: C₁₉H₂₆I₃N₃O₉

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 821.14

Ref: 3B-I0903

IOHEXOL CRS

CAS: 66108-95-0

IOHEXOL CRS

Formula: C₁₉H₂₆I₃N₃O₉

Molecular weight: 821.1379

Ref: 41-I0320800

IOHEXOL FOR PEAK IDENTIFICATION CRS

CAS: 66108-95-0

IOHEXOL FOR PEAK IDENTIFICATION CRS

Formula: C₁₉H₂₆I₃N₃O₉

Molecular weight: 821.1379

Ref: 41-Y0000672

Iohexol

CAS: 66108-95-0

Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof

Formula: C₁₉H₂₆I₃N₃O₉

Color and Shape: White Powder

Molecular weight: 820.88032

Ref: 45-1344600

Iohexol

CAS: 66108-95-0

Iohexol, a contrast agent, has an osmolality of 322-844 mOsm/kg, 1.1-3 times blood plasma's.

Formula: C₁₉H₂₆I₃N₃O₉

Purity: 99.61% - 99.89%

Color and Shape: White To Off-White Solid Powder

Molecular weight: 821.14

Ref: TM-T1554

Iohexol

CAS: 66108-95-0

Formula: C₁₉H₂₆I₃N₃O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 821.1379

Ref: IN-DA003R0Z

Iohexol

CAS: 66108-95-0

Iohexol

Purity: ≥80%

Molecular weight: 821.14g/mol

Ref: 54-BUP16812

N1,N3-Bis(2,3-Dihydroxypropyl)-5-(N-(2,3-Dihydroxypropyl)Acetamido)-2,4,6-Triiodoisophthalamide

CAS: 66108-95-0

N1,N3-Bis(2,3-Dihydroxypropyl)-5-(N-(2,3-Dihydroxypropyl)Acetamido)-2,4,6-Triiodoisophthalamide

Purity: 98%

Molecular weight: 821.14g/mol

Ref: 54-OR1014203

Iohexol

CAS: 66108-95-0

Formula: C₁₉H₂₆I₃N₃O₉

Purity: 98.0 - 102.0 % (anhydrous basis)

Color and Shape: White to off-white powder

Molecular weight: 821.14

Ref: 7W-GP9090

Iohexol, USP grade

CAS: 66108-95-0

Formula: C₁₉H₂₆I₃N₃O₉

Purity: 98.0 - 102.0 % (C19H26I3N3O9, anhydrous basis)

Color and Shape: White to off-white powder

Molecular weight: 821.14

Ref: 7W-GP7112

Iohexol

CAS: 66108-95-0

Formula: C₁₉H₂₆I₃N₃O₉

Color and Shape: Neat

Molecular weight: 821.14

Ref: 04-C14347000

Iohexol

CAS: 66108-95-0

Formula: C₁₉H₂₆I₃N₃O₉

Color and Shape: Neat

Molecular weight: 821.14

Ref: 86-MM1468.00

Iohexol

CAS: 66108-95-0

Formula: C₁₉H₂₆I₃N₃O₉

Molecular weight: 821.15

Ref: 4Z-I-371

Iohexol

Controlled Product

CAS: 66108-95-0

Applications Imaging agent.
References Wolf, G.L., et al.: Invest. Radiol., 16, 320 (1981), Mancini, G.B.J., et al.: Am. J. Cardiol., 51, 1218 (1983), Bettmann, M.A., et al.: Radiology, 153, 583 (1984), Sullivan, I.D., et al.: Br. Heart J.,51, 643 (1984),

Formula: C₁₉H₂₆I₃N₃O₉

Color and Shape: Off-White

Molecular weight: 821.14

Ref: TR-I729500

Iohexol

CAS: 66108-95-0

a contrast agent used in medical imaging such as angiography, CT scans, and MRI.

Formula: C₁₉H₂₆I₃N₃O₉

Purity: 98.0 To 102.0%

Color and Shape: White Powder

Molecular weight: 821.14 g/mol

Ref: 3D-FI24632

Iohexol

CAS: 66108-95-0

Purity: 98%

Molecular weight: 821.1420288

Ref: 10-F862815

N1-(2-(2,3-Dihydroxypropoxy)-3-hydroxypropyl Iohexol

CAS: 66108-95-0

Impurity Iohexol EP Impurity E
Applications N1-(2-(2,3-dihydroxypropoxy)-3-hydroxypropyl) Iohexol is an impurity of Iohexol (I729500), Imaging agent.
References Wolf, G.L., et al.: Invest. Radiol., 16, 320 (1981), Mancini, G.B.J., et al.: Am. J. Cardiol., 51, 1218 (1983), Bettmann, M.A., et al.: Radiology, 153, 583 (1984), Sullivan, I.D., et al.: Br. Heart J.,51, 643 (1984),

Formula: C₂₂H₃₂I₃N₃O₁₁

Color and Shape: Neat

Molecular weight: 895.22

Ref: TR-D493380

N1-(3-(2,3-Dihydroxypropoxy)-2-hydroxypropyl) Iohexol

Controlled Product

CAS: 66108-95-0

Impurity Iohexol EP Impurity D
Applications N1-(3-(2,3-dihydroxypropoxy)-2-hydroxypropyl) Iohexol is an impurity of Iohexol (I729500), Imaging agent.
References Wolf, G.L., et al.: Invest. Radiol., 16, 320 (1981), Mancini, G.B.J., et al.: Am. J. Cardiol., 51, 1218 (1983), Bettmann, M.A., et al.: Radiology, 153, 583 (1984), Sullivan, I.D., et al.: Br. Heart J.,51, 643 (1984),

Formula: C₂₂H₃₂I₃N₃O₁₁

Color and Shape: Off-White

Molecular weight: 895.22

Ref: TR-D493378

Iohexol-d3

Controlled Product

CAS: 66108-95-0

Formula: C₁₉D₃H₂₃I₃N₃O₉

Color and Shape: Neat

Molecular weight: 824.156

Ref: TR-I729503

Iohexol

CAS: 66108-95-0

Iohexol is a non-ionic, water-soluble radiopaque contrast agent, which is synthesized from iodinated organic compounds. With its high iodine content, Iohexol acts as an excellent medium for absorbing X-rays, thereby enhancing the contrast in radiographic images. The compound’s mode of action involves the attenuation of X-ray beams, with its iodine atoms providing the requisite density to create a contrast between different structures and fluids within the body.

Formula: C₁₉H₂₆I₃N₃O₉

Purity: Min. 98 Area-%

Molecular weight: 821.14 g/mol

Ref: 3D-Q-101936