CAS 66112-59-2

Temurtide

Description:

Temurtide, with the CAS number 66112-59-2, is a synthetic peptide that has garnered interest in the field of medicinal chemistry, particularly for its potential applications in cancer therapy. It is characterized by its specific amino acid sequence, which contributes to its biological activity. Temurtide functions as an immunomodulator, enhancing the immune response against tumor cells. Its mechanism of action involves the stimulation of T-cell activity, which is crucial for targeting and destroying cancerous cells. The substance is typically administered via injection and has been studied for its efficacy in treating certain types of tumors, including gliomas. In terms of stability, Temurtide is sensitive to environmental conditions, necessitating careful handling and storage. As with many peptides, its pharmacokinetics can be influenced by factors such as dosage, route of administration, and patient-specific variables. Overall, Temurtide represents a promising avenue in cancer immunotherapy, although further research is essential to fully understand its therapeutic potential and safety profile.

Formula: C₂₀H₃₄N₄O₁₂

InChI: InChI=1/C20H34N4O12/c1-7(26)13(19(33)23-10(17(21)31)4-5-12(28)29)24-18(32)8(2)35-16-14(22-9(3)27)20(34)36-11(6-25)15(16)30/h7-8,10-11,13-16,20,25-26,30,34H,4-6H2,1-3H3,(H2,21,31)(H,22,27)(H,23,33)(H,24,32)(H,28,29)/t7?,8?,10?,11-,13?,14-,15-,16-,20?/m1/s1

SMILES: CC(C(C(=NC(CCC(=O)O)C(=N)O)O)N=C(C(C)O[C@@H]1[C@H](C(O)O[C@H](CO)[C@H]1O)N=C(C)O)O)O

Synonyms:

• Temurtide [USAN:INN:BAN]
• N-Acetylmuramyl-threonyl-isoglutamine
• 2-Acetamido-3-O-(((1R)-1-((1S,2R)-1-(((1R)-1-carbamoyl-3-carboxypropyl)carbamoyl)-2-hydroxypropyl)carbamoyl)ethyl)-2-deoxy-D-glucopyranose
• D-alpha-Glutamine, N(sup 2)-(N-(N-acetylmuramoyl)-L-threonyl)-
• Drg-0177
• Rs-37449
• Temurtida
• Temurtida [INN-Spanish]
• Temurtidum
• Temurtidum [INN-Latin]
• Termurtide
• Threonyl MDP

Ac-muramyl-Thr-D-Glu-NH2

CAS: 66112-59-2

Muramyl dipeptide (MDP) is a cell-wall constituent of Mycobacterium tuberculosis, which induces an antibody response. Muramyl tripeptide (MTP) is a modified form of MDP that has been used as a vaccine adjuvant. Ac-muramyl-Thr-D-Glu-NH2 is a specific antibody to MDP, which can be reconstituted by mixing with water and sodium chloride. It binds to the influenza virus, enhancing the immune response. The flu virus contains an antigen that stimulates the production of antibodies against influenza virus, and it also contains amphipathic molecules that are responsible for receptor binding and fusion with cells in the respiratory system. Ac-muramyl-Thr-D-Glu-NH2 binds to these molecules and enhances their function by increasing the efficiency of antibody binding. This leads to increased viral clearance from the body and reduced symptoms associated with infection with influenza

Formula: C₂₀H₃₄N₄O₁₂

Purity: Min. 95%

Molecular weight: 522.5 g/mol

Ref: 3D-FA108289