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CAS 66138-05-4

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Diphenylethyltetrazoliumchloride

Description:
Diphenylethyltetrazolium chloride (DPTZ) is a chemical compound commonly used in biochemical assays, particularly in cell viability and proliferation studies. It is a tetrazolium salt that, upon reduction by viable cells, forms a colored formazan product, which can be quantitatively measured. DPTZ is characterized by its ability to penetrate cell membranes and its stability under physiological conditions. The compound is typically soluble in water and organic solvents, making it versatile for various experimental setups. Its application extends to assessing metabolic activity in cells, as only living cells can reduce the tetrazolium salt to its formazan form. Additionally, DPTZ is often utilized in research involving mitochondrial function and oxidative stress, as its reduction is closely linked to cellular respiration. Safety considerations should be taken into account when handling DPTZ, as with many chemical reagents, and proper laboratory protocols should be followed to ensure safe usage.
Formula:C15H15ClN4
InChI:InChI=1/C15H15N4.ClH/c1-2-15-16-18(13-9-5-3-6-10-13)19(17-15)14-11-7-4-8-12-14;/h3-12H,2H2,1H3;1H/q+1;/p-1
Synonyms:
  • 2,3-Diphenyl-5-ethyltetrazolium chloride
  • 5-ethyl-2,3-diphenyl-2H-tetrazol-3-ium chloride
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