CAS 6614-96-6

Cholesteryl sulfate, potassium salt

Description:

Cholesteryl sulfate, potassium salt is a chemical compound derived from cholesterol, where a sulfate group is esterified to the hydroxyl group of the cholesterol molecule, and it is associated with potassium ions. This compound typically appears as a white to off-white powder and is soluble in organic solvents, such as ethanol and methanol, but has limited solubility in water. It is often used in biochemical and pharmaceutical research due to its role in cell membrane dynamics and signaling pathways. Cholesteryl sulfate can influence lipid metabolism and has been studied for its potential implications in various biological processes, including cell proliferation and differentiation. As a sulfate ester, it may also exhibit surfactant properties, which can be relevant in formulations for drug delivery systems. Safety data should be consulted for handling and usage, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₅₄H₉₀KO₄S

InChI: InChI=1/C54H90O4S.K/c1-35(2)13-11-15-37(5)45-21-23-47-43-19-17-39-33-41(25-29-51(39,7)49(43)27-31-53(45,47)9)57-59(55,56)58-42-26-30-52(8)40(34-42)18-20-44-48-24-22-46(38(6)16-12-14-36(3)4)54(48,10)32-28-50(44)52;/h17-18,35-38,41-50H,11-16,19-34H2,1-10H3;/q;+1/t37-,38-,41+,42+,43+,44+,45-,46-,47+,48+,49+,50+,51+,52+,53-,54-;/m1./s1

SMILES: CC(C)CCCC(C)C1CCC2C3CC=C4CC(CCC4(C)C3CCC12C)OS(=O)(=O)OC1CCC2(C)C(=CCC3C4CCC(C(C)CCCC(C)C)C4(C)CCC23)C1.K

Synonyms:

• Cholesteryl potassium sulfate
• Potassium Cholesterol Sulfate
• Cholesterol Sulfate Potassium
• Cholesteryl sulfate potassium salt

Cholesteryl sulfate potassium salt

CAS: 6614-96-6

Cholesteryl sulfate potassium salt (CSK) is a solid lipid with a high melting point. It can be used as an active compound to form nanoparticles, which have the ability to penetrate cell membranes and enter cells. CSK has been shown to disrupt the lipid bilayer of cellular membranes, thereby releasing lipids such as cholesterol from the membrane surface. CSK also has polynucleotide binding properties that may lead to gene expression changes in cells. CSK is an anionic lipid, which makes it more likely to interact with negatively charged cell surfaces and membranes. Cholesteryl sulfate potassium salt has been shown to inhibit cholesterol synthesis in liver cells and increase LDL receptor activity in hepatocytes.

Formula: C₂₇H₄₅KO₄S

Purity: Min. 95%

Molecular weight: 504.81 g/mol

Ref: 3D-FC148002