CAS 6623-81-0

5-Methoxyuracil

Description:

5-Methoxyuracil is a pyrimidine derivative and a methylated form of uracil, characterized by the presence of a methoxy group at the 5-position of the uracil ring. Its molecular formula is C₅H₆N₂O₃, and it has a molecular weight of approximately 142.11 g/mol. This compound is typically a white to off-white crystalline solid, soluble in polar solvents such as water and methanol, but less soluble in non-polar solvents. 5-Methoxyuracil has garnered interest in biochemical research due to its potential role in nucleic acid metabolism and its effects on cellular processes. It may exhibit biological activity, including antitumor properties, and has been studied for its effects on RNA synthesis and cell proliferation. As with many chemical substances, handling 5-Methoxyuracil requires appropriate safety precautions, as it may pose health risks if ingested or inhaled. Its applications in research and potential therapeutic uses continue to be explored in the field of medicinal chemistry.

Formula: C₅H₆N₂O₃

InChI: InChI=1S/C5H6N2O3/c1-10-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)

InChI key: InChIKey=KELXHQACBIUYSE-UHFFFAOYSA-N

SMILES: O(C)C=1C(=O)NC(=O)NC1

Synonyms:

• 2,4-Dihydroxy-5-Methoxy Pyrimidine
• 2-chloro-6-oxo-7,8,9,10-tetrahydro-6H-benzo[c]chromen-3-yl cyclopropanecarboxylate
• 5-Methoxy-2,4(1H,3H)-pyrimidinedione
• 5-Methoxy-2,4-pyrimidinediol
• 5-Methoxy-pyrimidine-2,4-diol
• 5-Methoxypyrimidine-2,4-diol
• 5-Methoxyuracil
• 5-methoxypyrimidine-2,4(1H,3H)-dione
• NSC 55452
• Uracil, 5-methoxy-
• 2,4(1H,3H)-Pyrimidinedione, 5-methoxy-

5-Methoxyuracil (5-Methoxypyrimidine-2,4(1H,3H)-dione)

CAS: 6623-81-0

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Formula: C₅H₆N₂O₃

Color and Shape: White Powder

Molecular weight: 142.03784

Ref: 45-1A08120

2,4-Dihydroxy-5-methoxypyrimidine

CAS: 6623-81-0

Formula: C₅H₆N₂O₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 142.1127

Ref: IN-DA006OOG

Fluorouracil EP Impurity D

CAS: 6623-81-0

Formula: C₅H₆N₂O₃

Color and Shape: White To Off-White Solid

Molecular weight: 142.11

Ref: 4Z-F-535

5-Methoxyuracil

CAS: 6623-81-0

5-Methoxyuracil

Purity: 96%

Color and Shape: Solid

Molecular weight: 142.11g/mol

Ref: 54-OR480522

2,4-Dihydroxy-5-methoxypyrimidine

CAS: 6623-81-0

Formula: C₅H₆N₂O₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 142.11

Ref: 3B-D4599

5-Methoxypyrimidine-2,4(1H,3H)-dione (5-Methoxyuracil)

Controlled Product

CAS: 6623-81-0

Formula: C₅H₆N₂O₃

Color and Shape: Neat

Molecular weight: 142.11

Ref: 86-MM0593.04

5-METHOXYPYRIMIDINE-2,4-DIONE

CAS: 6623-81-0

Formula: C₅H₆N₂O₃

Purity: 97.0%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 142.114

Ref: 10-F300837

5-Methoxyuracil

CAS: 6623-81-0

Formula: MFCD₀₀₁₈

Purity: ≥ 96.0%

Color and Shape: White to almost white powder

Molecular weight: 142.11

Ref: 7W-GX2343

5-Methoxyuracil

Controlled Product

CAS: 6623-81-0

Impurity Fluorouracil EP Impurity D
Applications 5-Methoxyuracil (Fluorouracil EP Impurity D) is methoxylated uracil, a component of nucleid acid. 5-Methoxyuracil is used in the preparation of nucleosides.
References Vorbrueggen, H. et al.: Chem. Ber., 114, 1279 (1981); Novacek, A. et al.: Coll. Czech. Chem. Comm., 32, 1045 (1967);

Formula: C₅H₆N₂O₃

Color and Shape: Neat

Molecular weight: 142.11

Ref: TR-M271750

5-Methoxyuracil

CAS: 6623-81-0

5-Methoxyuracil is a labile, colorless and crystalline compound that occurs spontaneously in the presence of oxygen. It has a chemical structure similar to thiourea, with one methyl group substituted for the amino group on the heterocycle. 5-Methoxyuracil is used as a precursor for synthesis of thymine and uracil. It also acts as an antioxidant, preventing reactive oxygen species from causing cellular damage. 5-Methoxyuracil can be used in regenerative medicine to increase the production of messenger RNA (mRNA) and ribosomal RNA (rRNA). This drug is used as a prebiotic agent and can be synthetically produced by dimethylation of uridine followed by ethyl formate oxidation.

Formula: C₅H₆N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 142.11 g/mol

Ref: 3D-FM11934

Fluorouracil EP Impurity D

CAS: 6623-81-0

Formula: C₅H₆N₂O₃

Molecular weight: 142.1

Ref: ST-EA-CP-F32004

5-Methoxyuracil

CAS: 6623-81-0

2,4-Dihydroxy-5-methoxypyrimidine is a useful organic compound for research related to life sciences. The catalog number is T66505 and the CAS number is 6623-81-0.

Formula: C₅H₆N₂O₃

Color and Shape: Solid

Molecular weight: 142.114

Ref: TM-T66505