CAS 66233-46-3

Pregna-1,4-diene-3,20-dione, 6,12-difluoro-11-hydroxy-16-methyl-21-[(1-oxopentyl)oxy]-, (6α,11β,12α,16α)- (9CI)

Description:

Pregna-1,4-diene-3,20-dione, 6,12-difluoro-11-hydroxy-16-methyl-21-[(1-oxopentyl)oxy]-, (6α,11β,12α,16α)-, commonly referred to by its CAS number 66233-46-3, is a synthetic steroid compound characterized by its complex structure, which includes multiple functional groups such as hydroxyl, fluorine, and ether moieties. This compound is part of the broader class of corticosteroids, which are known for their anti-inflammatory and immunosuppressive properties. The presence of fluorine atoms enhances its biological activity and stability. The specific stereochemistry indicated by the (6α,11β,12α,16α) configuration suggests a particular three-dimensional arrangement that is crucial for its interaction with biological targets, such as steroid receptors. This compound may be utilized in pharmaceutical applications, particularly in the treatment of various inflammatory conditions or hormonal imbalances. However, its use and effects would depend on further pharmacological studies and regulatory approvals.

Formula: C₂₇H₃₆F₂O₅

Synonyms:

• Pregna-1,4-diene-3,20-dione, 6,12-difluoro-11-hydroxy-16-methyl-21-[(1-oxopentyl)oxy]-, (6α,11β,12α,16α)- (9CI)
• Fluocortolone Impurity 12

Fluocortolone Impurity 13

CAS: 66233-46-3

Formula: C₂₇H₃₆F₂O₅

Molecular weight: 478.58

Ref: 4Z-F-071031

(6α,​11β,​12α,​16α)​-6,​12-Difluoro-​11-​hydroxy-​16-​methyl-​21-​[(1-​oxopentyl)​oxy]​-pregna-​1,​4-​diene-​3,​20-​dione

Controlled Product

CAS: 66233-46-3

Formula: C₂₇H₃₆F₂O₅

Color and Shape: Neat

Molecular weight: 478.569

Ref: TR-D845960

Fluocortolone Impurity 13

Controlled Product

CAS: 66233-46-3

Fluocortolone Impurity 13 is a metabolite of fluorocortolone. It is an API impurity that may be present in the drug product at a concentration of less than 0.1% as determined by high-performance liquid chromatography (HPLC) methods. Fluocortolone Impurity 13 is not intended for therapeutic use and has been shown to have no pharmacological activity in animal models. Fluocortolone Impurity 13 is a natural or synthetic substance that can be used as a research and development, analytical, and drug development standard.

Formula: C₂₇H₃₆F₂O₅

Purity: Min. 95%

Molecular weight: 478.25308

Ref: 3D-IF180652

Diflucortolone Valerate Impurity 12

CAS: 66233-46-3

Formula: C₂₇H₃₆F₂O₅

Molecular weight: 478.58

Ref: ST-EA-CP-D115011