CAS 6628-86-0

5-Chloro-2-nitrobenzaldehyde

Description:

5-Chloro-2-nitrobenzaldehyde is an organic compound characterized by its aromatic structure, featuring a benzaldehyde functional group with both a chlorine and a nitro substituent. The presence of the chlorine atom at the 5-position and the nitro group at the 2-position on the benzene ring influences its reactivity and physical properties. This compound typically appears as a yellow to orange crystalline solid and is known for its moderate solubility in organic solvents such as ethanol and acetone, while being less soluble in water. It is often utilized in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals, due to its electrophilic nature, which allows it to participate in nucleophilic substitution reactions. Additionally, 5-Chloro-2-nitrobenzaldehyde can serve as an important intermediate in the synthesis of more complex organic molecules. Safety precautions should be observed when handling this compound, as it may pose health risks if inhaled or ingested, and appropriate personal protective equipment should be used.

Formula: C₇H₄ClNO₃

InChI: InChI=1S/C7H4ClNO3/c8-6-1-2-7(9(11)12)5(3-6)4-10/h1-4H

InChI key: InChIKey=SWGPIDCNYAYXMJ-UHFFFAOYSA-N

SMILES: C(=O)C1=C(N(=O)=O)C=CC(Cl)=C1

Synonyms:

• 2-nitro-5-Chlorobenzaldehyde
• 3-Chloro-6-nitrobenzaldehyde
• Benzaldehyde, 5-chloro-2-nitro-
• NSC 59734
• 5-Chloro-2-nitrobenzaldehyde

5-Chloro-2-nitrobenzaldehyde

CAS: 6628-86-0

Formula: C₇H₄ClNO₃

Purity: >98.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 185.56

Ref: 3B-C0217

5-Chloro-2-nitrobenzaldehyde

CAS: 6628-86-0

Formula: C₇H₄ClNO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 185.5646

Ref: IN-DA003MNK

5-Chloro-2-nitrobenzaldehyde

CAS: 6628-86-0

Purity: ≥ 98.0%

Color and Shape: Off-white to light yellow crystalline powder

Ref: 7W-GK6575

5-Chloro-2-nitrobenzaldehyde

CAS: 6628-86-0

5-Chloro-2-nitrobenzaldehyde

Formula: C₇H₄ClNO₃

Purity: ≥95%

Color and Shape: white to yellow solid

Molecular weight: 185.56g/mol

Ref: 54-OR1091

5-Chloro-2-nitrobenzaldehyde

CAS: 6628-86-0

Formula: C₇H₄ClNO₃

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 185.56

Ref: 10-F078021

5-Chloro-2-nitrobenzaldehyde

CAS: 6628-86-0

5-Chloro-2-nitrobenzaldehyde (5CNB) is a molecule that has been shown to inhibit the activity of tyrosinase, an enzyme involved in melanin production. 5CNB inhibits tyrosinase by binding to the aldehyde groups and nitro groups on its surface. This binding prevents hydrogen bonds from forming with tyrosine kinase, which is a protein responsible for the activation of tyrosinase. The compound has been shown to have antihypertensive effects in rats, as well as inhibit the transformation of blood pressure into heart rate variability. 5CNB does not reach high concentrations in humans when orally ingested, but can be detected in blood samples. It is also found at low levels in human urine and faeces. The compound has been shown to bind to melanocytes in vitro and may be used as a treatment for hyperpigmentation disorders such as melasma or chloasma.

Formula: C₇H₄ClNO₃

Purity: Min. 95%

Molecular weight: 185.56 g/mol

Ref: 3D-FC64008