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CAS 663-73-0

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2,2,3,3-Tetrafluoropropionyl chloride

Description:
2,2,3,3-Tetrafluoropropionyl chloride, with the CAS number 663-73-0, is a chemical compound characterized by its structure, which includes a propionyl group substituted with four fluorine atoms and a chlorine atom. This compound is typically a colorless to pale yellow liquid and is known for its reactivity, particularly as an acylating agent. It is used in organic synthesis, especially in the preparation of fluorinated compounds and pharmaceuticals. The presence of fluorine atoms imparts unique properties, such as increased lipophilicity and thermal stability, making it valuable in various chemical applications. Additionally, 2,2,3,3-Tetrafluoropropionyl chloride is sensitive to moisture and can hydrolyze in the presence of water, releasing hydrochloric acid and forming the corresponding acid. Safety precautions are essential when handling this compound due to its corrosive nature and potential health hazards, including irritation to the skin, eyes, and respiratory system. Proper storage and handling protocols should be followed to mitigate risks associated with its use.
Formula:C3HClF4O
InChI:InChI=1/C3HClF4O/c4-1(9)3(7,8)2(5)6/h2H
SMILES:C(=O)(C(C(F)F)(F)F)Cl
Synonyms:
  • 3H-Tetrafluoropropionyl chloride
  • 2,2,3,3-Tetrafluoropropanoyl Chloride
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