CAS 6633-40-5

7-nitro-9H-fluoren-2-ol

Description:

7-Nitro-9H-fluoren-2-ol is an organic compound characterized by its unique structure, which includes a fluorenyl moiety substituted with a nitro group and a hydroxyl group. This compound typically appears as a yellow to orange solid and is known for its potential applications in organic synthesis and as a fluorescent probe. The presence of the nitro group contributes to its electron-withdrawing properties, influencing its reactivity and solubility in various solvents. The hydroxyl group can participate in hydrogen bonding, enhancing its solubility in polar solvents. Additionally, 7-nitro-9H-fluoren-2-ol can exhibit interesting photophysical properties, making it useful in studies related to fluorescence and photochemistry. Its synthesis often involves nitration of fluoren-2-ol, followed by purification processes such as recrystallization. As with many nitro compounds, it is essential to handle 7-nitro-9H-fluoren-2-ol with care due to potential toxicity and environmental considerations.

Formula: C₁₃H₉NO₃

InChI: InChI=1/C13H9NO3/c15-11-2-4-13-9(7-11)5-8-6-10(14(16)17)1-3-12(8)13/h1-4,6-7,15H,5H2

InChI key: InChIKey=VFTOHJFKIJLYKN-UHFFFAOYSA-N

SMILES: N(=O)(=O)C=1C=C2C(C=3C(C2)=CC(O)=CC3)=CC1

Synonyms:

• 2-Hydroxy-7-nitrofluorene
• 7-Hydroxy-2-nitrofluorene
• 9H-fluoren-2-ol, 7-nitro-
• Fluoren-2-ol, 7-nitro-
• NSC 56690
• 7-Nitro-9H-fluoren-2-ol
• 7-Nitrofluoren-2-ol
• 2-Hydroxy-7-nitro-9H-fluorene
• 7-Nitro

7-Nitrofluoren-2-ol

Controlled Product

CAS: 6633-40-5

Applications A major metabolite of 2-nitrofluorene (NF). It exhibits a significant estrogenic activity.
References Stresser, D., et al.: Drug Metab. Dispos., 26, 868 (1998), Charles, G., et al.: Toxicol. Sci., 55, 320 (2000), Raichurkar, A., et al.: J. Med. Chem., 46, 4419 (2003).

Formula: C₁₃H₉NO₃

Color and Shape: Neat

Molecular weight: 227.22

Ref: TR-N495875