CymitQuimica logo

CAS 66335-39-5

:

5'-deoxy-5-fluoro-2',3'-o-isopropylideneuridine

Description:
5'-Deoxy-5-fluoro-2',3'-O-isopropylideneuridine, with the CAS number 66335-39-5, is a modified nucleoside that exhibits unique structural and chemical characteristics. This compound features a fluorine atom at the 5' position of the ribose sugar, which can influence its biological activity and stability. The isopropylidene group at the 2' and 3' positions protects the hydroxyl groups, enhancing the compound's stability against hydrolysis. This modification can also affect the nucleoside's interaction with enzymes and its incorporation into nucleic acids. The presence of the fluorine atom may impart antiviral properties, making it of interest in medicinal chemistry and drug development. Additionally, the compound's structural modifications can alter its solubility and permeability, which are critical factors in pharmacokinetics. Overall, 5'-deoxy-5-fluoro-2',3'-O-isopropylideneuridine serves as a valuable tool in biochemical research and therapeutic applications, particularly in the study of nucleoside analogs and their potential roles in treating viral infections or cancer.
Formula:C12H15FN2O5
InChI:InChI=1/C12H15FN2O5/c1-5-7-8(20-12(2,3)19-7)10(18-5)15-4-6(13)9(16)14-11(15)17/h4-5,7-8,10H,1-3H3,(H,14,16,17)/t5-,7+,8?,10-/m1/s1
Synonyms:
  • 1-[(4R,6R,6aS)-2,2,6-trimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-5-fluoro-pyrimidine-2,4-dione
  • 5'-deoxy-2',3'-O-isopropylidene-5-fluorouridine
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 5 products.