CAS 66340-28-1

Desacetylcefotaxime

Description:

Desacetylcefotaxime is a beta-lactam antibiotic that is a derivative of cefotaxime, primarily used in the treatment of bacterial infections. It exhibits a broad spectrum of activity against various Gram-positive and Gram-negative bacteria, making it effective in clinical settings. The compound is characterized by its ability to inhibit bacterial cell wall synthesis, which is a crucial mechanism for its antibacterial action. Desacetylcefotaxime is typically administered via injection and is known for its relatively high stability against certain beta-lactamases, enzymes produced by bacteria that can inactivate many antibiotics. Its pharmacokinetic properties include good tissue penetration and a moderate half-life, allowing for effective dosing regimens. Additionally, it is important to monitor for potential side effects, which may include allergic reactions or gastrointestinal disturbances. Overall, desacetylcefotaxime plays a significant role in the treatment of infections, particularly in cases where resistance to other antibiotics is a concern.

Formula: C₁₄H₁₅N₅O₆S₂

InChI: InChI=1S/C14H15N5O6S2/c1-25-18-7(6-4-27-14(15)16-6)10(21)17-8-11(22)19-9(13(23)24)5(2-20)3-26-12(8)19/h4,8,12,20H,2-3H2,1H3,(H2,15,16)(H,17,21)(H,23,24)/b18-7-/t8-,12-/m1/s1

InChI key: InChIKey=FHYWAOQGXIZAAF-GHXIOONMSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1CO)[H]

Synonyms:

• Deacetylcefotaxime
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-(hydroxymethyl)-8-oxo-, [6R-[6α,7β(Z)]]-
• (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-(hydroxymethyl)-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-(hydroxymethyl)-8-oxo-, (6R,7R)-

Desacetylcefotaxime

CAS: 66340-28-1

Formula: C₁₄H₁₅N₅O₆S₂

Purity: 97%

Molecular weight: 413.4288

Ref: IN-DA00FDC4

Cefotaxime EP Impurity B

CAS: 66340-28-1

Formula: C₁₄H₁₅N₅O₆S₂

Color and Shape: Pale Yellow Solid

Molecular weight: 413.42

Ref: 4Z-C-106004

Desacetylcefotaxime

CAS: 66340-28-1

Desacetylcefotaxime, a Cefotaxime metabolite, has strong antimicrobial effects against various bacteria.

Formula: C₁₄H₁₅N₅O₆S₂

Color and Shape: Solid

Molecular weight: 413.43

Ref: TM-T73902

Cefotaxime Sodium EP Impurity B

CAS: 66340-28-1

Formula: C₁₄H₁₅N₅O₆S₂

Molecular weight: 413.42

Ref: ST-EA-CP-C123002

3-Desacetyl Cefotaxime Potassium (>90%)

CAS: 66340-28-1

Applications 3-Desacetyl Cefotaxime Potassium Salt, is an impurity of Cefotaxime sodium (C242950).
References Amaker, R., et al.: Antimicrob. Agents Chemother., 40, 1139 (1996), Taylor, P., et al.: Clin. Biochem., 38, 328 (2005),

Formula: C₁₄H₁₄KN₅O₆S₂

Purity: >90%

Color and Shape: Neat

Molecular weight: 451.52

Ref: TR-D295530

3-Desacetylcefotaxime potassium

CAS: 66340-28-1

3-Desacetylcefotaxime potassium is an antimicrobial agent that belongs to the group of beta-lactam antibiotics.It si an active metabolite of cefotaxime and effective against various bacterial infections

Formula: C₁₄H₁₄N₅O₆S₂K

Purity: (%) Min. 95%

Color and Shape: White Powder

Molecular weight: 451.52 g/mol

Ref: 3D-FD157459