CAS 66341-16-0

2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl dihydrogen phosphate

Description:

2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl dihydrogen phosphate, with CAS number 66341-16-0, is a chemical compound that features a purine base structure, which is characteristic of nucleobases found in nucleic acids. This compound contains a methoxy group and a dihydrogen phosphate moiety, indicating its potential role in biochemical processes, particularly in relation to nucleotides and nucleic acids. The presence of the amino and oxo groups suggests that it may participate in hydrogen bonding and other interactions, influencing its solubility and reactivity. Typically, such compounds can exhibit biological activity, potentially serving as intermediates in metabolic pathways or as substrates for enzymatic reactions. Its structural complexity may also imply specific interactions with biological macromolecules, making it of interest in medicinal chemistry and biochemistry. Overall, this compound's characteristics suggest it could play a role in cellular processes, although specific applications would depend on further research and context.

Formula: C₈H₁₄N₅O₇P

InChI: InChI=1/C8H11N5O3.H3O4P/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14;1-5(2,3)4/h3,14H,1-2,4H2,(H3,9,11,12,15);(H3,1,2,3,4)

SMILES: C(COCn1cnc2c1[nH]c(=N)nc2O)O.OP(=O)(O)O

Synonyms:

• 2-Amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one phosphate (1:1)
• 6H-purin-6-one, 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-, phosphate (1:1) (salt)
• Acycloguanosine monophosphate
• 2-amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one phosphate (salt)

Acyclovir monophosphate

CAS: 66341-16-0

Formula: C₈H₁₂N₅O₆P

Color and Shape: Solid

Molecular weight: 305.1845

Ref: IN-DA006NA2

2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl dihydrogen phosphate

CAS: 66341-16-0

2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl dihydrogen phosphate

Purity: ≥95%

Molecular weight: 305.18g/mol

Ref: 54-OR9250T

Acyclovir Monophosphate

CAS: 66341-16-0

Stability Hygroscopic
Applications A nucleoside analog phosphates for topical use in the treatment of herpes virus infections. A topical treatment that seems to bypass a key mechanism responsible for resistance to Acyclovir.
References Furman, P., et al.: J. Virol., 32, 72 (1979), Darby, G., et al.: J. Gen. Virol., 48, 451 (1980),Prisbe, E., et al.: J. Med. Chem., 29, 671 (1986), Ellis, M., et al.: Antimicrob. Agents Chemother., 33, 304 (1989),

Formula: C₈H₁₂N₅O₆P

Color and Shape: Off-White

Molecular weight: 305.18

Ref: TR-A192500

Acyclovir monophosphate

CAS: 66341-16-0

Acyclovir is a prodrug that is converted in vivo to its active form, acyclovir monophosphate. Acyclovir monophosphate inhibits DNA synthesis by human macrophages and other cells infected with viruses. Acyclovir inhibits the activity of the human enzyme, DNA polymerase. It binds reversibly to the viral DNA polymerase, preventing it from binding to the viral DNA and synthesizing new viral DNA strands. The hydroxyl group on acyclovir monophosphate reacts with the 3'-hydroxyl group on the terminal nucleotide of each dNTP, which prevents further elongation of the strand and thus blocks viral replication. Acyclovir also inhibits other enzymes that are important for cell metabolism, such as RNA polymerases and protein kinases. Acyclovir has minimal toxicity in humans and can be used as a diagnostic agent for hepatitis virus infections or as an antiviral agent for treating wild-type

Formula: C₈H₁₂N₅O₆P

Purity: (%) Min. 95%

Color and Shape: Powder

Molecular weight: 305.19 g/mol

Ref: 3D-FA07187

Acyclovir Monophosphate

CAS: 66341-16-0

Formula: C₈H₁₂N₅O₆P

Molecular weight: 305.18

Ref: ST-EA-CP-A8053

Acyclovir monophosphate

CAS: 66341-16-0

Acyclovir monophosphate, a strong anti-HSV agent, inhibits viral DNA polymerase, blocking DNA synthesis and chain elongation.

Formula: C₈H₁₂N₅O₆P

Color and Shape: Solid

Molecular weight: 305.18

Ref: TM-T60709