CAS 66357-35-5

Ranitidine

Description:

Ranitidine is a medication that belongs to the class of histamine H2-receptor antagonists, primarily used to reduce stomach acid production. It is commonly prescribed for conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. The chemical formula of ranitidine is C13H22N4O3S, and it features a furan ring, a thiazole ring, and an amine group, contributing to its pharmacological activity. Ranitidine is known for its ability to competitively inhibit the binding of histamine to H2 receptors on gastric parietal cells, thereby decreasing gastric acid secretion. It is typically administered orally or intravenously and has a relatively rapid onset of action. However, ranitidine has faced scrutiny and regulatory action due to concerns about impurities linked to potential carcinogenic effects, leading to its withdrawal from many markets. Despite its effectiveness in managing acid-related disorders, patients are advised to consult healthcare professionals for alternative treatments and to discuss any potential risks associated with its use.

Formula: C₁₃H₂₂N₄O₃S

InChI: InChI=1S/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3

InChI key: InChIKey=VMXUWOKSQNHOCA-UHFFFAOYSA-N

SMILES: C(N(C)C)C=1OC(CSCCNC(=CN(=O)=O)NC)=CC1

Synonyms:

• Label
• Midaven
• N-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N′-methyl-2-nitro-1,1-ethenediamine
• Ranitidin
• Ranitidina
• Ranitidine
• Ulcerit
• Zenetac
• 1,1-Ethenediamine, N-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-N'-methyl-2-nitro-
• 1,1-Ethenediamine, N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N′-methyl-2-nitro-
• 266-332-5
• N-{2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}-N'-methyl-2-nitroethene-1,1-diamine
• (Z)-N-{2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}-N'-methyl-2-nitroethene-1,1-diamine
• (E)-N-{2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}-N'-methyl-2-nitroethene-1,1-diamine
• Ranitidine base

{2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}[(E)-1-(methylamino)-2-nitroethenyl]amine

CAS: 66357-35-5

Formula: C₁₃H₂₂N₄O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 314.4038

Ref: IN-DA0035KB

Ranitidine

CAS: 66357-35-5

Ranitidine

Purity: ≥98%

Molecular weight: 314.4g/mol

Ref: 54-BUP15584

Ranitidine

CAS: 66357-35-5

Formula: C₁₃H₂₂N₄O₃S

Molecular weight: 314.40

Ref: 7W-GP1033

Ranitidine

CAS: 66357-35-5

Formula: C₁₃H₂₂N₄O₃S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 314.40

Ref: 3B-R0261

Ranitidine

CAS: 66357-35-5

Ranitidine (HSDB 3925) is a non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors).

Formula: C₁₃H₂₂N₄O₃S

Purity: 99.52%

Color and Shape: Solid Solid

Molecular weight: 314.40

Ref: TM-T3610

Ranitidine

CAS: 66357-35-5

Applications Ranitidine (cas# 66357-35-5) was used as a standard for testing the therapeutic effect of brown propolis extract against aspirin and ethanol- induced gastric ulcers.
References Patil, M., et al.: Eur. J. Biomed. Pharma. Sci., 7, 620 (2020)

Formula: C₁₃H₂₂N₄O₃S

Color and Shape: Neat

Molecular weight: 314.40

Ref: TR-R120023

Ranitidine - Bio-X ™

CAS: 66357-35-5

Ranitidine is classified as a histamine antagonist that reduces gastric acid section by blocking the H2- receptor. It decreases the amount of acid in the stomach. It is used to treat conditions such as ulcers, Zollinger-Ellison syndrome and GERD.

Formula: C₁₃H₂₂N₄O₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 314.4 g/mol

Ref: 3D-BR166204

Ranitidine

CAS: 66357-35-5

Histamine receptor H2 antagonist

Formula: C₁₃H₂₂N₄O₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 314.4 g/mol

Ref: 3D-FR65147