CAS 663599-11-9

1-(4-((3-(dimethylcarbamoyl)pyridin-4-yl)disulfanyl)pentanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid

CAS: 663599-11-9

Formula: C₁₇H₂₁N₃O₈S₃

Molecular weight: 491.5589

Ref: IN-DA01EN15

Sulfo-DMAC-SPP

CAS: 663599-11-9

Sulfo-DMAC-SPP is an ADC linker employed for the synthesis of antibody-drug conjugates (ADCs) [1].

Formula: C₁₇H₂₁N₃O₈S₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 491.56

Ref: TM-T18724

Sulfo-dmac-spp

CAS: 663599-11-9

Sulfo-DMAC-SPP is a type of disulfide-containing linker, a classification of cleavable linkers. It is designed to be highly stable in the bloodstream but can be cleaved inside the target cancer cell. The sulfonated linker increases the water solubility of the conjugate, which improves its pharmacokinetics and can reduce off-target toxicity.

Formula: C₁₇H₂₁N₃O₈S₃

Purity: Min. 95%

Molecular weight: 491.6 g/mol

Ref: 3D-NBB59911