CAS 6639-99-2

α-Dihydroequilenin

Description:

α-Dihydroequilenin is a naturally occurring steroid and a member of the class of compounds known as phytoestrogens, which are plant-derived compounds with estrogenic activity. It is primarily derived from the roots of the wild yam (Dioscorea species) and is structurally related to equilin, another steroid. The compound exhibits a phenolic structure, which contributes to its biological activity. α-Dihydroequilenin is known for its potential effects on hormone regulation and has been studied for its role in alleviating menopausal symptoms and promoting bone health. It is often used in hormone replacement therapies and dietary supplements. The substance is characterized by its ability to bind to estrogen receptors, mimicking the effects of estrogen in the body, which can influence various physiological processes. Additionally, α-Dihydroequilenin is subject to various metabolic pathways, which can affect its bioavailability and efficacy. As with many phytoestrogens, its safety and effectiveness can vary based on individual health conditions and should be approached with caution in therapeutic contexts.

Formula: C₁₈H₂₀O₂

InChI: InChI=1/C18H20O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h2-5,10,16-17,19-20H,6-9H2,1H3/t16-,17+,18-/m0/s1

InChI key: InChIKey=RYWZPRVUQHMJFF-KSZLIROESA-N

SMILES: C[C@@]12[C@](C=3C(=C4C(=CC3)C=C(O)C=C4)CC1)(CC[C@H]2O)[H]

Synonyms:

• (17Alpha)-Estra-1,3,5(10),6,8-Pentaene-3,17-Diol
• (17α)-Estra-1,3,5,7,9-pentaene-3,17-diol
• 17alpha-Dihydroequilenin
• 17α-Dihydroequilenin
• Estra-1,3,5(10),6,8-Pentaene-3,17-Diol
• Estra-1,3,5(10),6,8-pentaene-3,17alpha-diol (8CI)
• Estra-1,3,5(10),6,8-pentaene-3,17α-diol
• Estra-1,3,5,7,9-pentaene-3,17-diol, (17α)-
• Estra-1,3,5,7,9-pentaene-3,17alpha-diol
• Nsc 12171
• alfa-Dihydroequilenina
• alfa-Dihydroequilenina [Spanish]
• alpha-Dihydroequilenin
• alpha-Dihydroequilenina
• alpha-Dihydroequilenina [Spanish]
• alpha-Estra-1,3,5,7,9-pentaen-3,17-diol
• α-Dihydroequilenin
• Estra-1,3,5,7,9-pentaene-3,17α-diol
• Equilenin 17a-Dihydro Impurity
• 17α-Dihydro Equilenin
• 17a-Dihydro Equilenin
• Estra-1,3,5,7,9-pentene-3,17α-diol
• Equilenin Impurity 3
• &frac12

17-α-Dihydro Equilenin

CAS: 6639-99-2

Formula: C₁₈H₂₀O₂

Color and Shape: Yellow Solid

Molecular weight: 268.36

Ref: 4Z-E-316

17a-Dihydro Equilenin

Controlled Product

CAS: 6639-99-2

Applications The 17α-metabolite of Equilin (E592800).
References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),

Formula: C₁₈H₂₀O₂

Color and Shape: Neat

Molecular weight: 268.35

Ref: TR-D448955

17α-Dihydro Equilenin

Controlled Product

CAS: 6639-99-2

17α-Dihydroequilenin is a synthetic analogue of equilenin, which is the 17-hydroxy metabolite of estradiol. It binds to estrogen receptors, but does not cause transcriptional activation or the induction of pro-apoptotic proteins. 17α-Dihydroequilenin has been shown to be effective in the treatment of autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. The drug has also been shown to have anti-inflammatory and anti-cancer effects in animal models. The drug may be used for hormone therapy in women, because it has a low potential for carcinogenic activity.

Formula: C₁₈H₂₀O₂

Purity: Min. 95%

Molecular weight: 268.35 g/mol

Ref: 3D-GAA63999

17α-Dihydro Equilenin

CAS: 6639-99-2

Formula: C₁₈H₂₀O₂

Molecular weight: 268.36

Ref: ST-EA-CP-E26008