CAS 66490-33-3

4-Chlorobenzo[b]thiophene

Description:

4-Chlorobenzo[b]thiophene is an organic compound characterized by its fused ring structure, which consists of a benzene ring and a thiophene ring, with a chlorine substituent at the 4-position of the benzene ring. This compound typically appears as a pale yellow to light brown solid and is known for its aromatic properties, contributing to its stability and reactivity. It is relatively insoluble in water but soluble in organic solvents, making it useful in various chemical applications. The presence of the chlorine atom enhances its electrophilic character, allowing it to participate in substitution reactions. 4-Chlorobenzo[b]thiophene is of interest in the fields of organic synthesis and materials science, particularly in the development of organic semiconductors and as a potential building block for pharmaceuticals. Its unique structure and properties make it a subject of study in both synthetic and applied chemistry. Safety precautions should be observed when handling this compound, as with many chlorinated organic substances, due to potential toxicity and environmental concerns.

Formula: C₈H₅ClS

InChI: InChI=1S/C8H5ClS/c9-7-2-1-3-8-6(7)4-5-10-8/h1-5H

InChI key: InChIKey=YGYUMNQONHLLNC-UHFFFAOYSA-N

SMILES: ClC1=C2C(=CC=C1)SC=C2

Synonyms:

• 4-Chlorobenzothiophene
• 4-Chlorobenzo[b]thiophene
• Benzo[b]thiophene, 4-chloro-
• 4-chlorobenzothiophene
• 4-chloro-Benzo[b]thiophene
• 4-chloro- Benzo[b]thiophene ISO 9001：2015 REACH
• 4-chloro-1-benzothiophene

4-Chlorobenzothiophene

CAS: 66490-33-3

Formula: C₈H₅ClS

Purity: 97%

Color and Shape: Solid

Molecular weight: 168.6433

Ref: IN-DA0036U1

4-Chlorobenzo[b]thiophene

CAS: 66490-33-3

4-Chlorobenzo[b]thiophene

Purity: 98%

Molecular weight: 168.65g/mol

Ref: 54-OR75229

Brexpiprazole Impurity 84

CAS: 66490-33-3

Formula: C₈H₅ClS

Molecular weight: 168.64

Ref: 4Z-B-115093

4-Chlorobenzo[b]thiophene

CAS: 66490-33-3

Formula: C₈H₅ClS

Purity: 97%

Color and Shape: Solid

Molecular weight: 168.64

Ref: 10-F053803

4-Chlorobenzothiophene

Controlled Product

CAS: 66490-33-3

Applications 4-Chlorobenzothiophene is an intermediate used to prepare 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism.
References Takeuchi, K., et al.: Bioorg. Med. Chem. Lett., 13, 1903 (2003)

Formula: C₈H₅ClS

Color and Shape: Neat

Molecular weight: 168.64

Ref: TR-C364180