CAS 66493-39-8

4-(boc-amino)benzoic acid

Description:

4-(Boc-amino)benzoic acid, with the CAS number 66493-39-8, is a chemical compound characterized by the presence of a benzoic acid moiety substituted with a tert-butyloxycarbonyl (Boc) protected amino group at the para position. This compound typically appears as a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethyl sulfoxide, but less soluble in water. The Boc group serves as a protective group for the amino functionality, making it useful in peptide synthesis and other organic reactions where selective deprotection is required. The compound exhibits typical acid-base properties due to the carboxylic acid group, allowing it to participate in various chemical reactions, including esterification and amidation. Its structure enables it to engage in hydrogen bonding, influencing its reactivity and interactions in biological systems. Overall, 4-(Boc-amino)benzoic acid is a valuable intermediate in organic synthesis, particularly in the development of pharmaceuticals and biologically active compounds.

Formula: C₁₂H₁₄NO₄

InChI: InChI=1/C12H15NO4/c1-12(2,3)17-11(16)13-9-6-4-8(5-7-9)10(14)15/h4-7H,1-3H3,(H,13,16)(H,14,15)/p-1

SMILES: CC(C)(C)OC(=O)Nc1ccc(cc1)C(=O)[O-]

Synonyms:

• Boc-4-Abz-OH
• (1S)-1-(biphenyl-4-yl)ethanaminium
• (1R)-1-(biphenyl-4-yl)ethanaminium
• 4-[(Tert-Butoxycarbonyl)Amino]Benzoic Acid
• 4-[(Tert-Butoxycarbonyl)Amino]Benzoate
• N-tert-Butoxycarbonyl-4-aminobenzoic acid

4-(tert-Butoxycarbonylamino)benzoic Acid

CAS: 66493-39-8

Formula: C₁₂H₁₅NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 237.26

Ref: 3B-B3898

Boc-4-Abz-OH

CAS: 66493-39-8

Formula: C₁₂H₁₅NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 237.2518

Ref: IN-DA003OFF

N-Boc-4-aminobenzoic acid

CAS: 66493-39-8

N-Boc-4-aminobenzoic acid

Purity: 98%

Molecular weight: 237.25g/mol

Ref: 54-OR307084

Boc-4-Abz-OH

CAS: 66493-39-8

Formula: C₁₂H₁₅NO₄

Molecular weight: 237.26

Ref: 7W-GM9481

Boc-p-Aminobenzoic Acid

CAS: 66493-39-8

Boc-p-Aminobenzoic Acid is an extracellular peptidase inhibitor that has been shown to be damaging to cells. It is a conjugate of p-aminobenzoic acid with the unusual amino acid Boc, which inhibits the activity of proteinases and peptidases. This drug is used for the treatment of emphysema, an autoimmune disease, and prostate carcinoma. It has also been shown to inhibit the growth of some tumor cells by blocking cell division and DNA synthesis. The enzyme carbonic anhydrase II (CAII) is responsible for the conversion of carbon dioxide into bicarbonate ions in tissues. Boc-p-Aminobenzoic Acid can inhibit CAII, which may lead to tissue damage or death.

Formula: C₁₂H₁₅NO₄

Purity: Min. 95%

Molecular weight: 237.26 g/mol

Ref: 3D-BAB-5403-PI

4-tert-Butoxycarbonylamino-benzoic acid

CAS: 66493-39-8

Formula: C₁₂H₁₅NO₄

Purity: 97%

Color and Shape: Solid, Beige powder

Molecular weight: 237.255

Ref: 10-F021366

4-(N-tert-Butoxycarbonyl)aminobenzoic Acid-d4

Controlled Product

CAS: 66493-39-8

Applications Isotope labelled 4-(N-tert-Butoxycarbonyl)aminobenzoic Acid is the tert-Butyloxycarbonyl group protected derivative of 4-Aminobenzoic Acid (A591500), an widely distributed B complex factor in nature.
References Robbins, M.L., et al.: J. Immunol., 64, 431 (1950), Roshick, C., et al.: J. Biol. Chem., 275, 38111 (2000), He, J., et al.: Chem. Biol., 10, 1225 (2003), Jiang, W., et al.: Science, 316, 1188 (2007), Zocher, G., et al.: J. Mol. Biol., 373, 65 (2007),

Formula: C₁₂D₄H₁₁NO₄

Color and Shape: Neat

Molecular weight: 241.276

Ref: TR-B690842