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CAS 665-66-7

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Amantadine hydrochloride

Description:
Amantadine hydrochloride is a synthetic compound primarily used as an antiviral medication and an antiparkinsonian agent. It is classified as an adamantane derivative and exhibits a unique structure characterized by a bicyclic framework. The substance is a white to off-white crystalline powder that is soluble in water and exhibits a pH range that is typically neutral to slightly acidic. Amantadine hydrochloride functions by inhibiting the replication of certain viruses, particularly influenza A, and is also believed to enhance dopaminergic activity in the brain, making it useful in treating Parkinson's disease and drug-induced extrapyramidal symptoms. The compound has a relatively low toxicity profile, but it can cause side effects such as insomnia, dizziness, and gastrointestinal disturbances. Its mechanism of action involves blocking the M2 ion channel of the influenza virus, thereby preventing viral uncoating. Additionally, it is important to monitor patients for potential interactions with other medications, as amantadine can affect the central nervous system.
Formula:C10H17N·ClH
InChI:InChI=1S/C10H17N.ClH/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;/h7-9H,1-6,11H2;1H
InChI key:InChIKey=WOLHOYHSEKDWQH-UHFFFAOYSA-N
SMILES:NC12CC3CC(C1)CC(C2)C3.Cl
Synonyms:
  • (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine
  • 1-Adamantamine hydrochloride
  • 1-Adamantylamine Hydrochloride
  • 1-Amantadine hydrochloride
  • 1-Aminoadamantane hydrochloride
  • Adamantanamine hydrochloride
  • Adamantylamine hydrochloride
  • Adamin
  • Adamine
  • Ads 5102
  • See more synonyms
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