CAS 66521-38-8

N-[1,1,2,2-tetradeuterio-2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide

Description:

N-[1,1,2,2-tetradeuterio-2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, with CAS number 66521-38-8, is a deuterated derivative of a compound related to indole and acetamide. This substance features a tetradeuterated ethyl group, which means that it contains four deuterium atoms, enhancing its stability and altering its physical properties compared to its non-deuterated counterpart. The presence of the methoxy group on the indole ring contributes to its potential biological activity, as indole derivatives are often studied for their pharmacological properties. The acetamide functional group suggests that this compound may exhibit characteristics typical of amides, such as hydrogen bonding capabilities, which can influence its solubility and reactivity. Deuterated compounds are frequently used in NMR spectroscopy and other analytical techniques due to their unique spectral signatures. Overall, this compound may be of interest in medicinal chemistry and research applications, particularly in studies involving isotopic labeling and drug development.

Formula: C₁₃H₁₂D₄N₂O₂

InChI: InChI=1/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)/i5D2,6D2

SMILES: CC(=NC(C(c1c[nH]c2ccc(cc12)OC)([2H])[2H])([2H])[2H])O

Synonyms:

• acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl-1,1,2,2-d4
• N-[2-(5-Methoxy-1H-indol-3-yl)(2

Melatonin-d4

CAS: 66521-38-8

Formula: C₁₃H₁₂D₄N₂O₂

Molecular weight: 236.31

Ref: 4Z-M-762

N-Acetyl-5-methoxytryptamine-α,α,β,β-d4

CAS: 66521-38-8

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 236.31

Ref: 3U-D2952

Melatonin-d4

CAS: 66521-38-8

Melatonin D5, a deuterium-labeled version of melatonin, is a hormone produced by the pineal gland, known for its role as a selective ATF-6 inhibitor that promotes apoptosis in human hepatoma cells via COX-2 downregulation. Additionally, it activates melatonin receptors and exhibits antioxidative and anti-inflammatory properties.

Formula: C₁₃H₁₆N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 236.3

Ref: TM-T11995

Melatonin-d4

Controlled Product

CAS: 66521-38-8

Applications Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.
References Barchas, et al.: Nature, 214, 919 (1967), Glass, J.D., et al.: Science, 214, 821 (1981),

Formula: C₁₃₂H₄H₁₂N₂O₂

Color and Shape: Off-White To Beige

Molecular weight: 236.30

Ref: TR-M215002

N-ACETYL-5-METHOXYTRYPTAMINE-α,α,β,β-D4

CAS: 66521-38-8

Formula: C₁₃H₁₂D₄N₂O₂

Purity: 95.87%

Color and Shape: Solid

Molecular weight: 236.3030

Ref: IN-DA00FBOW