CAS 66521-66-2

4-(3-Pyridinyl)-2-aminopyrimidine

Description:

4-(3-Pyridinyl)-2-aminopyrimidine, identified by its CAS number 66521-66-2, is a heterocyclic organic compound featuring a pyrimidine ring substituted with an amino group and a pyridine moiety. This compound typically exhibits characteristics common to aminopyrimidines, such as being a solid at room temperature, with potential for solubility in polar solvents due to the presence of the amino group. Its structure suggests it may participate in hydrogen bonding, influencing its reactivity and interactions with biological targets. The pyridine ring contributes to its aromaticity and may enhance its electronic properties, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. Compounds like this can exhibit various biological activities, including potential roles as kinase inhibitors or in other therapeutic applications. Additionally, the presence of nitrogen atoms in both the pyrimidine and pyridine rings can affect the compound's basicity and overall stability. As with many heterocycles, the specific characteristics can vary based on the environment and conditions under which the compound is studied.

Formula: C₉H₈N₄

InChI: InChI=1/C9H8N4/c10-9-12-5-3-8(13-9)7-2-1-4-11-6-7/h1-6H,(H2,10,12,13)

SMILES: c1cc(cnc1)c1cc[nH]c(=N)n1

Synonyms:

• 4-(3-Pyridinyl)-2-pyrimidinamine
• 4-(3-Piridinyl)-2-Pirimidine Amine
• 4-(Pyridin-3-Yl)Pyrimidin-2-Amine
• 4-(3-Pyridinyl)-2-pyrimidine amine
• 4-(3-PYRIDINYL)-2-PYRIMIDINYLAMINE
• 4-Pyridin-3-yl-pyriMidin-2-ylaMine
• 4-(3-Pyridinyl)-2-pyrimidine amine, 97%, reagent grade
• BUTTPARK 41\09-83
• 2-PyriMidinaMine,4-(3-pyridinyl)-
• 4-(3-Pyridinyl)-2-aminopyrimidine
• 4-(3-Pyridyl)-2-pyrimidinamine
• 4-(3-Pyridinyl)-2-pyrimidine amine ,97%
• 4-(3-Pyridyl)-2-pyrimidineamine
• )-2-pyrimidine amine
• 2-Amino-4-(3-pyridyl)pyrimidine
• 2-amino-4-(3-pyridinyl)-pyrimidine
• 4-(3-Pyridinyl)-2-aminopyrimidine ISO 9001：2015 REACH

4-(Pyridin-3-yl)pyrimidin-2-amine

CAS: 66521-66-2

Formula: C₉H₈N₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 172.1866

Ref: IN-DA0036WB

4-(3-Pyridinyl)-2-pyrimidine amine

CAS: 66521-66-2

4-(3-Pyridinyl)-2-pyrimidine amine

Purity: 98%

Molecular weight: 172.19g/mol

Ref: 54-OR965482

4-(Pyridin-3-yl)pyrimidin-2-ylamine

CAS: 66521-66-2

Color and Shape: Neat

Ref: 86-MM3374.08

4-(Pyridin-3-yl)pyrimidin-2-amine

CAS: 66521-66-2

Formula: C₉H₈N₄

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 172.19

Ref: 3B-P2666

4-(Pyridin-3-yl)pyrimidin-2-amine

CAS: 66521-66-2

Formula: C₉H₈N₄

Molecular weight: 172.19

Ref: ST-EA-CP-N11019

2-Amino-4-(3-pyridinyl)-pyrimidine

CAS: 66521-66-2

Formula: C₉H₈N₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 172.191

Ref: 10-F048155

4-(3-Pyridinyl)-2-pyrimidinamine

Controlled Product

CAS: 66521-66-2

Applications Intermediate in the preparation of Nilotinib.
References Bennett, G., et al.: J. Med. Chem., 21, 623 (1978)

Formula: C₉H₈N₄

Color and Shape: Neat

Molecular weight: 172.19

Ref: TR-P991700

4-(3-Pyridinyl)-2-pyrimidine amine

CAS: 66521-66-2

Dasatinib is a cancer drug that belongs to the group of drugs called tyrosine kinase inhibitors. Dasatinib inhibits the growth of cells by binding to an enzyme called epidermal growth factor receptor (EGFR) which activates cell division and proliferation. Dasatinib binds to the EGFR and prevents it from receiving signals from other molecules such as epidermal growth factor, leading to the death of cancer cells. Dasatinib has been shown to be effective in treating chronic myeloid leukemia, acute lymphoblastic leukemia, and Philadelphia chromosome-positive acute lymphoblastic leukemia in adults. Dasatinib is also used in the treatment of solid tumors that are resistant to other anticancer agents.

Formula: C₉H₈N₄

Purity: Min. 95%

Molecular weight: 172.19 g/mol

Ref: 3D-NP57381