CAS 66564-14-5

Cinitapride

Description:

Cinitapride is a pharmaceutical compound primarily used as a gastroprokinetic agent, which means it enhances gastrointestinal motility. It belongs to the class of substituted benzamides and is characterized by its ability to act as a selective antagonist of certain serotonin receptors, particularly 5-HT4, while also exhibiting some affinity for 5-HT3 receptors. This dual action helps in alleviating symptoms associated with gastrointestinal disorders, such as dyspepsia and functional gastrointestinal disorders. Cinitapride is typically administered orally and is known for its relatively low side effect profile compared to other prokinetic agents. Its chemical structure includes a benzamide moiety, contributing to its pharmacological properties. The compound is soluble in organic solvents but has limited solubility in water, which can influence its formulation and delivery in pharmaceutical applications. Overall, Cinitapride's unique mechanism of action and favorable safety profile make it a valuable option in the management of gastrointestinal motility disorders.

Formula: C₂₁H₃₀N₄O₄

InChI: InChI=1S/C21H30N4O4/c1-2-29-20-13-18(22)19(25(27)28)12-17(20)21(26)23-16-8-10-24(11-9-16)14-15-6-4-3-5-7-15/h3-4,12-13,15-16H,2,5-11,14,22H2,1H3,(H,23,26)

InChI key: InChIKey=ZDLBNXXKDMLZMF-UHFFFAOYSA-N

SMILES: C(NC1CCN(CC2CCC=CC2)CC1)(=O)C3=C(OCC)C=C(N)C(N(=O)=O)=C3

Synonyms:

• 4-Amino-N-(1-(3-cyclohexen-1-ylmethyl)-4-piperidyl)-2-ethoxy-5-nitrobenzamide
• 4-Amino-N-[1-(3-cyclohexen-1-ylmethyl)-4-piperidinyl]-2-ethoxy-5-nitrobenzamide
• 4-amino-N-[1-(cyclohex-3-en-1-ylmethyl)piperidin-4-yl]-2-ethoxy-5-nitrobenzamide
• Benzamide, 4-amino-N-[1-(3-cyclohexen-1-ylmethyl)-4-piperidinyl]-2-ethoxy-5-nitro-
• Cinitaprida
• Cinitaprida [INN-Spanish]
• Cinitapride [INN]
• Cinitapridum
• Cinitapridum [INN-Latin]
• Unii-R8I97I2L24
• Cinitapride

Cinitapride

CAS: 66564-14-5

Formula: C₂₁H₃₀N₄O₄

Molecular weight: 402.49

Ref: 7W-GP6046

Cinitapride

CAS: 66564-14-5

Cinitapride

Purity: ≥98%

Molecular weight: 402.49g/mol

Ref: 54-BUP02370

Cinitapride

CAS: 66564-14-5

Formula: C₂₁H₃₀N₄O₄

Color and Shape: Yellow Solid

Molecular weight: 402.50

Ref: 4Z-C-157001

Cinitapride-d5

CAS: 66564-14-5

Formula: C₂₁H₂₅D₅N₄O₄

Color and Shape: Yellow Solid

Molecular weight: 407.53

Ref: 4Z-C-157002

Cinitapride

CAS: 66564-14-5

Cinitapride (Blaston) treats acid reflux and gastric issues, targeting 5-HT2, 5-HT1, and 5-HT4 receptors.

Formula: C₂₁H₃₀N₄O₄

Purity: 99.52%

Color and Shape: Solid

Molecular weight: 402.49

Ref: TM-T21385

Cinitapride

CAS: 66564-14-5

Applications A novel prokinetic benzamide-stimulating gastrointestinal motility agent and antiucer agent. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors (1,2,3).
References (1) Alarcon de la Lastra, C. et al.: Pharmacol, 54, 193 (1997)(2) Robert, M. et al.: Drug Metab. Disp., 35, 1149 (2007)(3) Alarcon de la Lastra, C. et al.: Inflam. Res., 47, 131 (1998)

Formula: C₂₁H₃₀N₄O₄

Color and Shape: Neat

Molecular weight: 402.49

Ref: TR-C441990

Cinitapride

CAS: 66564-14-5

5-HT1 and 5-HT4 receptor agonist; 5-HT2 receptor antagonist

Formula: C₂₁H₃₀N₄O₄

Purity: Min. 95%

Color and Shape: Yellow Solid

Molecular weight: 402.49 g/mol

Ref: 3D-FC20445

Cinitapride

CAS: 66564-14-5

Formula: C₂₁H₃₀N₄O₄

Molecular weight: 402.49

Ref: ST-EA-CP-C270010