CAS 6659-45-6

(2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethyl)[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one

Description:

The chemical substance known as (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethyl)[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, with the CAS number 6659-45-6, is a complex organic compound characterized by its intricate polycyclic structure. This substance features multiple functional groups, including methoxy groups, which contribute to its chemical reactivity and potential biological activity. The stereochemistry indicated by the R and S designations suggests specific spatial arrangements of atoms, which can significantly influence the compound's properties and interactions. It is likely to exhibit solubility in organic solvents due to its hydrophobic nature, while its molecular structure may allow for interactions with biological targets, making it of interest in pharmacological research. The presence of multiple rings and substituents suggests potential applications in medicinal chemistry, particularly in the development of novel therapeutic agents. However, detailed studies would be necessary to fully understand its properties, including its stability, reactivity, and biological effects.

Formula: C₂₃H₂₄O₆

InChI: InChI=1S/C23H24O6/c1-11(2)16-8-14-15(28-16)6-5-12-22(24)21-13-7-18(25-3)19(26-4)9-17(13)27-10-20(21)29-23(12)14/h5-7,9,11,16,20-21H,8,10H2,1-4H3/t16-,20-,21+/m1/s1

InChI key: InChIKey=DTFARBHXORYQBF-HBGVWJBISA-N

SMILES: O=C1C=2C(=C3C(O[C@@H](C(C)C)C3)=CC2)O[C@]4([C@@]1(C=5C(OC4)=CC(OC)=C(OC)C5)[H])[H]

Synonyms:

• [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethyl)-, [2R-(2α,6aα,12aα)]-
• [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aαH)-one, 1,2,12,12aα-tetrahydro-2α-isopropyl-8,9-dimethoxy-
• [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethyl)-, (2R,6aS,12aS)-
• Dihydrorotenone
• (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethyl)[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one

1',2'-Dihydrorotenone

CAS: 6659-45-6

Formula: C₂₃H₂₄O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 396.4331

Ref: IN-DA00FGMF

Dihydrorotenone

CAS: 6659-45-6

Dihydrorotenone

Purity: ≥98%

Molecular weight: 396.43g/mol

Ref: 54-BUP00511

Dihydrorotenone

CAS: 6659-45-6

Formula: C₂₃H₂₄O₆

Molecular weight: 396.44

Ref: 7W-GY5563

Dihydrorotenone

CAS: 6659-45-6

Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome. It induces human plasma cell apoptosis by provoking endoplasmic reticulum stress and induces cell death by activating the p38 but not the JNK signaling pathway.

Formula: C₂₃H₂₄O₆

Purity: 95%~99%

Molecular weight: 396.439

Ref: BP-BP3939

Dihydrorotenone

CAS: 6659-45-6

Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.

Formula: C₂₃H₂₄O₆

Purity: 98.98% - 99.58%

Color and Shape: Solid

Molecular weight: 396.43

Ref: TM-TN1586

Dihydrorotenone

CAS: 6659-45-6

Dihydrorotenone is a natural product that has been shown to have anti-cancer and anti-inflammatory effects. It inhibits the production of reactive oxygen species, inhibits the p38 signaling pathway, and reduces the mitochondrial membrane potential. Dihydrorotenone is also an inhibitor of endoplasmic reticulum stress and is a diagnostic agent that can be used to identify metabolic disorders. This compound has been shown to inhibit mitochondrial respiratory chain enzymes in animals. Dihydrorotenone binds with high affinity to the ATP synthase enzyme in mitochondria, inhibiting ATP synthesis and causing cell death by lowering the mitochondrial membrane potential.

Formula: C₂₃H₂₄O₆

Purity: Min. 95%

Molecular weight: 396.4 g/mol

Ref: 3D-GAA65945