CAS 66592-87-8: Cefadroxil monohydrate
Description:Cefadroxil monohydrate is a semisynthetic antibiotic belonging to the cephalosporin class, primarily used to treat bacterial infections. It is characterized by its broad-spectrum activity against both Gram-positive and Gram-negative bacteria, making it effective for various infections, including those of the skin, respiratory tract, and urinary system. The chemical structure of cefadroxil includes a beta-lactam ring, which is essential for its antibacterial action, as it inhibits bacterial cell wall synthesis. Cefadroxil monohydrate appears as a white to off-white crystalline powder and is soluble in water, which facilitates its formulation in oral dosage forms. The monohydrate form indicates that it contains one molecule of water for each molecule of cefadroxil, influencing its stability and solubility. Commonly administered orally, cefadroxil is generally well-tolerated, though potential side effects may include gastrointestinal disturbances and allergic reactions. Its pharmacokinetics involve absorption in the gastrointestinal tract, with peak plasma concentrations occurring within a few hours post-administration.
Formula:C16H17N3O5S·H2O
InChI:InChI=1S/C16H17N3O5S.H2O/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8;/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24);1H2/t10-,11-,15-;/m1./s1
InChI key:InChIKey=NBFNMSULHIODTC-CYJZLJNKSA-N
SMILES:O=C(O)C1=C(C)CSC2N1C(=O)C2NC(=O)C(N)C3=CC=C(O)C=C3.O
- Synonyms:
- (6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate (1:1)
- (6R,7R)-7-{[amino(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- (6R,7R)-7-{[amino(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo, monohydrate, (6R-(6alpha,7beta(R*)))-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-, hydrate (1:1), (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-, monohydrate, (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[amino(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-, monohydrate, [6R-[6α,7β(R*)]]-
- 7-{[Amino(4-Hydroxyphenyl)Acetyl]Amino}-3-Methyl-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
- Cefadroxil Micronised Powder
- Duricef
- See more synonyms
- Ultracef
- Cefadroxil monohydrate