CAS 66647-41-4

Z-Gly-Pro-Arg-4M.beta.NA

Description:

Z-Gly-Pro-Arg-4M.beta.NA, also known by its CAS number 66647-41-4, is a synthetic peptide that consists of a sequence of amino acids, specifically glycine (Gly), proline (Pro), and arginine (Arg), with a protective Z (benzyloxycarbonyl) group and a modification at the arginine position. This compound is often utilized in biochemical and pharmaceutical research due to its potential applications in drug development and peptide synthesis. The Z group serves to protect the amino group of the glycine residue during synthesis, enhancing stability and solubility. The presence of the arginine residue contributes to the peptide's overall charge and can influence its interaction with biological membranes and proteins. Additionally, the 4M.beta.NA modification may refer to a specific structural or functional alteration that enhances the peptide's properties. Overall, Z-Gly-Pro-Arg-4M.beta.NA is characterized by its stability, solubility, and potential bioactivity, making it a valuable compound in various scientific applications.

Formula: C₃₂H₃N₇O₆

Z-Gly-Pro-Arg-4MβNA

CAS: 66647-41-4

Z-GPR-MNA, a thrombin substrate which has been modeled after a thrombin cleavage site in human fibrinogen, can be used for a sensitive assay of antithrombin III activity. Z-GPR-MNA is also cleaved by cathepsin K and granzyme A and, according to Valchanov et al., a most efficient substrate for the demonstration of rat mast cell tryptase in histochemistry. Stock solutions of this substrate are best prepared in DMSO.

Formula: C₃₂H₃₉N₇O₆

Purity: 99.8%

Color and Shape: Beige Powder

Molecular weight: 617.71

Ref: 01-4003347

Z-Gly-Pro-Arg-4MβNA

CAS: 66647-41-4

Z-Gly-Pro-Arg-4MβNA is a thrombin substrate that, upon cleavage by thrombin, releases 4-methoxy-2-naphthylamine (4MβNA).

Formula: C₃₂H₃₉N₇O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 617.7

Ref: TM-T80115

N-A-Cbz-glycyl-L-prolyl-L-arginine-4-Me-B-nph

CAS: 66647-41-4

N-Acetyl-Cbz-glycyl-L-prolyl-L-arginine-4-MeBnph is a peptide that is an activator of the ion channel TRPV1. It has been shown to be a potent agonist of the TRPV1 receptor, which has been implicated in pain, inflammation, and cell proliferation. The peptide also inhibits the interaction of the acetylcholine receptor with its ligand in rat brain synaptosomes. N-Acetyl-Cbz-glycyl-L-prolyl-L-arginine 4MeBnph also activates voltage gated calcium channels and inhibits protein interactions by binding to the receptor site on cell membranes.

Formula: C₃₄H₄₃N₇O₈

Purity: Min. 95%

Molecular weight: 677.7 g/mol

Ref: 3D-RCA64741