CAS 66715-65-9

Pyridine-2-sulfonyl chloride

Description:

Pyridine-2-sulfonyl chloride, with the CAS number 66715-65-9, is an aromatic sulfonyl chloride derived from pyridine. It features a pyridine ring substituted with a sulfonyl chloride group at the 2-position. This compound is typically a colorless to pale yellow liquid and is known for its strong odor. Pyridine-2-sulfonyl chloride is highly reactive, particularly due to the presence of the sulfonyl chloride functional group, which can readily participate in nucleophilic substitution reactions. It is commonly used as a reagent in organic synthesis, particularly for the introduction of sulfonyl groups into various substrates. Additionally, it can serve as an intermediate in the preparation of pharmaceuticals and agrochemicals. Due to its reactivity, it should be handled with care, as it can be corrosive and may cause irritation to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment, are essential when working with this compound.

Formula: C₅H₄ClNO₂S

InChI: InChI=1/C5H4ClNO2S/c6-10(8,9)5-3-1-2-4-7-5/h1-4H

SMILES: c1ccnc(c1)S(=O)(=O)Cl

Synonyms:

• 2-Pyridinesulfonyl chloride

Pyridine-2-sulfonyl chloride

CAS: 66715-65-9

Formula: C₅H₄ClNO₂S

Purity: 95%

Color and Shape: Liquid

Molecular weight: 177.6088

Ref: IN-DA00FASR

Pyridine-2-sulphonyl chloride

CAS: 66715-65-9

Pyridine-2-sulphonyl chloride

Purity: 90%

Molecular weight: 177.61g/mol

Ref: 54-OR1003505

Vonoprazan Impurity 42

CAS: 66715-65-9

Formula: C₅H₄ClNO₂S

Molecular weight: 177.60

Ref: 4Z-V-051044

Pyridin-2-sulfonyl chloride

CAS: 66715-65-9

Pyridin-2-sulfonyl chloride is a kinase receptor inhibitor that binds to and inhibits the activity of certain protein kinases. It is used in the treatment of cardiovascular disorders and can be administered intravenously or orally. Pyridin-2-sulfonyl chloride has been shown to inhibit tumor necrosis factor-α (TNF-α) production in vivo, which may be due to its ability to inhibit the release of proinflammatory cytokines from macrophages. This drug also has pharmacokinetic properties that are similar to those of other sulfonamides, with an elimination half life of about 2 hours. Pyridin-2-sulfonyl chloride is not reactive with amines, which makes it a useful reagent for organic synthesis.

Formula: C₅H₄ClNO₂S

Purity: Min. 95%

Color and Shape: Colorless Clear Liquid

Molecular weight: 177.61 g/mol

Ref: 3D-FP106500

2-Pyridinesulfonyl chloride

CAS: 66715-65-9

Formula: C₅H₄ClNO₂S

Purity: 95%

Color and Shape: Liquid, Clear

Molecular weight: 177.6

Ref: 10-F067903

2-Pyridinesulfonyl Chloride, Technical Grade

Controlled Product

CAS: 66715-65-9

Formula: C₅H₄ClNO₂S

Color and Shape: Neat

Molecular weight: 177.61

Ref: TR-P991550