CAS 66722-44-9

Bisoprolol

Description:

Bisoprolol is a selective beta-1 adrenergic antagonist, primarily used in the management of hypertension and heart failure. It belongs to the class of medications known as beta-blockers, which work by blocking the effects of adrenaline on the heart, leading to a decrease in heart rate and blood pressure. Chemically, bisoprolol is characterized by its structure, which includes a phenol ring and a side chain that contributes to its selectivity for beta-1 receptors. It is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. Bisoprolol is well-absorbed in the gastrointestinal tract, with a bioavailability that can be influenced by first-pass metabolism. Common side effects may include fatigue, dizziness, and bradycardia, while contraindications include severe asthma and certain heart conditions. Overall, bisoprolol is an effective therapeutic agent for cardiovascular conditions, with a favorable safety profile when used appropriately.

Formula: C₁₈H₃₁NO₄

InChI: InChI=1/C18H31NO4/c1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4/h5-8,14-15,17,19-20H,9-13H2,1-4H3

InChI key: InChIKey=VHYCDWMUTMEGQY-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)C)O)C1=CC=C(COCCOC(C)C)C=C1

Synonyms:

• 1-(Propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol
• 1-(p-2-Isopropoxyethoxymethylphenoxy)-3-isopropylaminopropan-2-ol
• 1-[4-(2-Isopropoxy-ethoxymethyl)-phenoxy]-3-isopropylamino-propan-2-ol
• 1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol
• 2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-
• Bisoprolol
• Bisoprolol base
• Cardensiel
• Konkor
• Racemic Bisoprolol
• Ty 0201
• Bisoprolol(Hemifumalate)
• 1-[(1-Methylethyl)amino]-3-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-2-propanol
• 1-[4-[[2-(1-Methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol-d5
• (R)-1-[(1-Methylethyl)amino]-3-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-2-propanol
• (R)-1-(Isopropylamino)-3-[4-(2-isopropoxyethoxymethyl)phenoxy]-2-propanol
• Bisoprolol-D5
• 1-[4-[2-(1-Methylethoxy)ethoxymethyl]phenoxy]-3-(1-methylethylamino)propan-2-ol
• Bisoprolo
• (S)-1-(Isopropylamino)-3-[4-(2-isopropoxyethoxymethyl)phenoxy]-2-propanol
• (S)-1-[(1-Methylethyl)amino]-3-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-2-propanol

Bisoprolol Hemifumarate

CAS: 104344-23-2, 66722-44-9

Formula: C₁₈H₃₁NO₄C₄H₄O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 383.49

Ref: 3B-B3994

Bisoprolol

CAS: 66722-44-9

Formula: C₁₈H₃₁NO₄

Molecular weight: 325.45

Ref: 4Z-B-0949

Bisoprolol

CAS: 66722-44-9

Formula: C₁₈H₃₁NO₄

Molecular weight: 325.44

Ref: 7W-GP6636

Bisoprolol

CAS: 66722-44-9

Formula: C₁₈H₃₁NO₄

Color and Shape: Light Yellow

Molecular weight: 325.44

Ref: 86-MM0460.00

Cardensiel

Controlled Product

CAS: 66722-44-9

Formula: C₁₈H₃₁NO₄

Color and Shape: Neat

Molecular weight: 325.44

Ref: TR-C667250

Bisoprolol

CAS: 66722-44-9

Formula: C₁₈H₃₁NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 325.4430

Ref: IN-DA006IOH

Bisoprolol

Controlled Product

CAS: 66722-44-9

Bisoprolol is a selective beta-adrenergic receptor antagonist that is used to treat high blood pressure and congestive heart failure. It also has a protective effect on the myocardium. Bisoprolol blocks the action of catecholamines on beta-2 receptors in the heart and peripheral vascular system, reducing heart rate, cardiac output, and blood pressure. This drug also inhibits calcium release from the sarcoplasmic reticulum of cardiac muscle cells by binding to the ryanodine receptor. Bisoprolol is not absorbed when taken orally, so it must be administered by injection or intravenously. The drug’s activity can be monitored using chromatographic analysis to measure levels of bisoprolol in human serum or blood pressure monitoring to measure changes in blood pressure after administration of bisoprolol.

Formula: C₁₈H₃₁NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 325.44 g/mol

Ref: 3D-FB170138