CAS 66757-27-5

2-Palmitoyl-sn-glycero-3-phosphocholine

Description:

2-Palmitoyl-sn-glycero-3-phosphocholine, commonly referred to as palmitoyl phosphatidylcholine, is a phospholipid that plays a crucial role in cellular membranes. It is characterized by a glycerol backbone esterified with two fatty acid chains, one of which is palmitic acid, and a phosphate group linked to a choline moiety. This structure imparts amphiphilic properties, allowing it to form bilayers in aqueous environments, which is essential for membrane integrity and fluidity. The substance is typically found in biological membranes, contributing to membrane dynamics and signaling processes. It is also utilized in various applications, including drug delivery systems and as a component in liposomes. In terms of physical properties, it is generally a white to off-white solid or powder at room temperature, soluble in organic solvents, and exhibits stability under physiological conditions. Its role in biochemistry and cell biology makes it a subject of interest in research related to membrane biology and lipid metabolism.

Formula: C₂₄H₅₀NO₇P

InChI: InChI=1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)32-23(21-26)22-31-33(28,29)30-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1

InChI key: InChIKey=NEGQHKSYEYVFTD-HSZRJFAPSA-N

SMILES: [C@@H](COP(OCC[N+](C)(C)C)(=O)[O-])(OC(CCCCCCCCCCCCCCC)=O)CO

Synonyms:

• 3,5,8-Trioxa-4-phosphatetracosan-1-aminium, 4-hydroxy-7-(hydroxymethyl)-N,N,N-trimethyl-9-oxo-, inner salt, 4-oxide, (R)-
• 2-Palmitoyl-sn-glycero-3-phosphocholine
• 3,5,8-Trioxa-4-phosphatetracosan-1-aminium, 4-hydroxy-7-(hydroxymethyl)-N,N,N-trimethyl-9-oxo-, inner salt, 4-oxide, (7R)-

2-Palmitoyl-sn-glycero-3-phosphocholine

CAS: 66757-27-5

Formula: C₂₄H₅₀NO₇P

Color and Shape: Solid

Molecular weight: 495.6301

Ref: IN-DA00FDGS

1-Hydroxy-2-Palmitoyl-sn-Glycero-3-Phosphatidylcholine

CAS: 66757-27-5

Formula: C24H50NO7P

Purity: >99%

Color and Shape: Solid

Molecular weight: 495.63

Ref: 48-38-1620

Choline Impurity 4

CAS: 66757-27-5

Formula: C₂₄H₅₀NO₇P

Color and Shape: White To Off-White Solid

Molecular weight: 495.63

Ref: 4Z-C-5944

2-Palmitoyl-sn-glycero-3-phosphocholine

Controlled Product

CAS: 66757-27-5

Applications Food preservative, having the ability to form complexes with starch, retarding its retrodegradation during storage.
References Yu, S., et al.: J. Agric. Food Chem., 54, 4482 (2006),

Formula: C₂₄H₅₀NO₇P

Color and Shape: Neat

Molecular weight: 495.64

Ref: TR-P157350

2-Palmitoyl-sn-glycero-3-phosphocholine-d31

Controlled Product

CAS: 66757-27-5

Applications 2-Palmitoyl-sn-glycero-3-phosphocholine-d31 is labelled 2-Palmitoyl-sn-glycero-3-phosphocholine (P157350) which is a food preservative, having the ability to form complexes with starch, retarding its retrodegradation during storage.
References Yu, S., et al.: J. Agric. Food Chem., 54, 4482 (2006)

Formula: C₂₄D₃₁H₁₉NO₇P

Color and Shape: Neat

Molecular weight: 526.821

Ref: TR-P157352

2-Palmitoyl-sn-glycero-3-phosphocholine

CAS: 66757-27-5

2-Palmitoyl-sn-glycero-3-phosphocholine is a phospholipid that functions in the cell membrane by providing a barrier to prevent water from penetrating the bilayer. It is also involved in energy metabolism and is an endogenous substance. 2-Palmitoyl-sn-glycero-3-phosphocholine has been shown to inhibit influenza virus replication, which may be due to its ability to hydrate the viral envelope, making it more permeable. This molecule has also been shown to bind with other lipids, forming phosphatidylcholine bilayers that are present in all cells of the body. The phosphatidylcholine bilayers provide a physical barrier between cells and may regulate the transfer of endogenous substances between cells.

Formula: C₂₄H₅₀NO₇P

Purity: Min. 95%

Molecular weight: 495.63 g/mol

Ref: 3D-FP26738